Adenocarcinoma in situ coexisting with carcinoma in situ of the cervix during pregnancy

Adenocarcinoma in situ coexisting with carcinoma in situ of the cervix during pregnancy

We report a pregnant patient with adenocarcinoma in situ (AIS) coexisting with carcinoma in situ (CIS) of the cervix diagnosed by conization at 16 weeks' gestation. Apoptotic activity was higher in the CIS lesion than in the AIS lesion in the cone biopsy specimen. Postpartum evaluation confirme...

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Veröffentlicht in:Archives of gynecology and obstetrics 2004-09, Vol.270 (2), p.116-118
Hauptverfasser: Nagaishi, Miwa, Fujiwaki, Ritsuto, Hata, Kohkichi, Makihara, Ken, Yamane, Yoshio, Miyazaki, Kohji
Format: Artikel
Sprache:eng
Schlagworte:
Adenocarcinoma - diagnosis
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Adult
Apoptosis
Carcinoma in Situ - diagnosis
Carcinoma in Situ - pathology
Carcinoma in Situ - surgery
Cerclage, Cervical
Colposcopy
Conization
Female
Gestational Age
Humans
Hysterectomy
Immunohistochemistry
In Situ Nick-End Labeling
Laser Therapy
Neoplasms, Multiple Primary - diagnosis
Neoplasms, Multiple Primary - pathology
Neoplasms, Multiple Primary - surgery
Pregnancy
Pregnancy Complications, Neoplastic - diagnosis
Pregnancy Complications, Neoplastic - pathology
Pregnancy Complications, Neoplastic - surgery
Uterine Cervical Neoplasms - diagnosis
Uterine Cervical Neoplasms - pathology
Uterine Cervical Neoplasms - surgery
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Beschreibung
Zusammenfassung:We report a pregnant patient with adenocarcinoma in situ (AIS) coexisting with carcinoma in situ (CIS) of the cervix diagnosed by conization at 16 weeks' gestation. Apoptotic activity was higher in the CIS lesion than in the AIS lesion in the cone biopsy specimen. Postpartum evaluation confirmed the disappearance of CIS lesion with positive cone margins, however, multifocal AIS with negative cone margins was found. Clinical course and biological features of AIS associated with pregnancy may be different from those of CIS.
ISSN:0932-0067
1432-0711
DOI:10.1007/s00404-002-0469-2