Aptamer-Functionalized Au Nanoparticles for the Amplified Optical Detection of Thrombin

The catalytic enlargement of aptamer-functionalized Au nanoparticles amplifies the optical detection of aptamer−thrombin complexes in solution and on surfaces.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American Chemical Society 2004-09, Vol.126 (38), p.11768-11769
Hauptverfasser:	Pavlov, Valeri, Xiao, Yi, Shlyahovsky, Bella, Willner, Itamar
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology Gold - chemistry Humans Hydrolases Immunoglobulin G - analysis Immunoglobulin G - chemistry Nanostructures - chemistry Oligonucleotides - chemistry Optics and Photonics Sensitivity and Specificity Serum Albumin - analysis Serum Albumin - chemistry Spectrum Analysis - methods Thrombin - analysis
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Beschreibung
Zusammenfassung:	The catalytic enlargement of aptamer-functionalized Au nanoparticles amplifies the optical detection of aptamer−thrombin complexes in solution and on surfaces.
ISSN:	0002-7863 1520-5126
DOI:	10.1021/ja046970u