Analytical correlation between plasma N-terminal pro-brain natriuretic peptide and brain natriuretic peptide in patients presenting with dyspnea

We examined the analytical correlation N-terminal pro-brain natriuretic peptide (NT-proBNP) and brain natriuretic peptide (BNP). Electrochemiluminescence and fluorescence immunoassays were used to measure NT-proBNP and BNP levels, respectively. The analytical correlation was satisfactory using the e...

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Veröffentlicht in:	Clinical biochemistry 2004-10, Vol.37 (10), p.933-936
Hauptverfasser:	Alibay, Yasmin, Beauchet, Alain, Mahmoud, Rami El, Brun-Ney, Dominique, Alexandre, Jeanne-Armelle, Benoit, Marie-Odile, Dubourg, Olivier, Aegerter, Philippe, Boileau, Catherine, Jondeau, Guillaume, Puy, Hervé
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Brain natriuretic peptide Dyspnea - blood Dyspnea - diagnosis Electrochemistry Female Fluorescence Humans Immunoassay Luminescent Measurements Male N-terminal pro-brain natriuretic peptide Natriuretic Peptide, Brain - blood Nerve Tissue Proteins - blood Non-radiometric assay Peptide Fragments - blood Prognosis Reproducibility of Results Sensitivity and Specificity
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Zusammenfassung:	We examined the analytical correlation N-terminal pro-brain natriuretic peptide (NT-proBNP) and brain natriuretic peptide (BNP). Electrochemiluminescence and fluorescence immunoassays were used to measure NT-proBNP and BNP levels, respectively. The analytical correlation was satisfactory using the equation: NT-proBNP = 8.56 × BNP + 91.7 and a correlation r = 0.85. The correlation was not influenced by age, gender and BMI of patients. We conclude that NT-proBNP correlates with BNP.
ISSN:	0009-9120 1873-2933
DOI:	10.1016/j.clinbiochem.2004.06.009