Impact of Anemia in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention: Analysis from the Controlled Abciximab and Device Investigation to Lower Late Angioplasty complications (CADILLAC) trial

We sought to investigate the impact of anemia in patients with acute myocardial infarction (AMI) undergoing primary percutaneous coronary intervention (PCI). The prognostic importance of anemia on primary PCI outcomes is unknown. In the Controlled Abciximab and Device Investigation to Lower Late Ang...

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Veröffentlicht in:	Journal of the American College of Cardiology 2004-08, Vol.44 (3), p.547-553
Hauptverfasser:	NIKOLSKY, Eugenia, AYMONG, Eve D, STUCKEY, Thomas, TURCO, Mark, COHEN, David A, NEGOITA, Manuela, LANSKY, Alexandra J, STONE, Gregg W, HALKIN, Amir, GRINES, Cindy L, COX, David A, GARCIA, Eulogio, MEHRAN, Roxana, TCHENG, James E, GRIFFIN, John J, GUAGLIUMI, Giulio
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anemia Anemia - complications Anemias. Hemoglobinopathies Angioplasty Angioplasty, Balloon, Coronary - adverse effects Angioplasty, Balloon, Coronary - mortality Antibodies, Monoclonal - therapeutic use Aspirin Biological and medical sciences Blood Component Transfusion - statistics & numerical data Cardiology Cardiology. Vascular system Confidence intervals Coronary heart disease Diabetes Diseases of red blood cells Diseases of the cardiovascular system Female Heart Heart attacks Hematocrit Hematologic and hematopoietic diseases Hemorrhage - etiology Hemorrhage - prevention & control Hospital costs Hospital Mortality Hospitalization Humans Hypertension Immunoglobulin Fab Fragments - therapeutic use Incidence Ischemia Male Medical prognosis Medical sciences Middle Aged Mortality Multivariate Analysis Myocardial Infarction - complications Myocardial Infarction - mortality Myocardial Infarction - therapy Platelet Aggregation Inhibitors - therapeutic use Predictive Value of Tests Prognosis Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Randomized Controlled Trials as Topic Stents - adverse effects Stroke Stroke - etiology Stroke - prevention & control Survival Analysis Treatment Outcome Variables Veins & arteries Women
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Zusammenfassung:	We sought to investigate the impact of anemia in patients with acute myocardial infarction (AMI) undergoing primary percutaneous coronary intervention (PCI). The prognostic importance of anemia on primary PCI outcomes is unknown. In the Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications (CADILLAC) trial, 2,082 patients of any age with AMI within 12 h onset undergoing primary PCI were randomized to balloon angioplasty versus stenting, each +/- abciximab. Outcomes were stratified by the presence of anemia at baseline, as defined by World Health Organization criteria (hematocrit
ISSN:	0735-1097 1558-3597
DOI:	10.1016/j.jacc.2004.03.080