ACUTE RETINAL NECROSIS IN PRIMARY HERPES SIMPLEX VIRUS TYPE I INFECTION

Here we report the case of an immunocompetent 8-year-old child who developed acute retinal necrosis concomitant with a primary herpes simplex virus type I infection. Ocular inflammation changed along with the development of a specific antibody titer in the serum. This evidence suggests that the immu...

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Veröffentlicht in:	The Pediatric infectious disease journal 2009-02, Vol.28 (2), p.163-164
Hauptverfasser:	Mora, Paolo, Guex-Crosier, Yan, Kamberi, Erilda, Orsoni, Jelka G
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyclovir - therapeutic use Anterior Chamber - pathology Anti-Inflammatory Agents - therapeutic use Antiviral Agents - therapeutic use Biological and medical sciences Child Fundus Oculi Herpes Simplex - complications Herpesvirus 1, Human - genetics Herpesvirus 1, Human - immunology Herpesvirus 1, Human - isolation & purification Human viral diseases Humans Immunocompetence Infectious diseases Male Medical sciences Prednisone - therapeutic use Retina - pathology Retina - virology Retinal Necrosis Syndrome, Acute - complications Retinal Necrosis Syndrome, Acute - virology Viral diseases Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye
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Zusammenfassung:	Here we report the case of an immunocompetent 8-year-old child who developed acute retinal necrosis concomitant with a primary herpes simplex virus type I infection. Ocular inflammation changed along with the development of a specific antibody titer in the serum. This evidence suggests that the immune response of the host can significantly modulate the clinical aspect of the ocular infection.
ISSN:	0891-3668 1532-0987
DOI:	10.1097/INF.0b013e318186258f