Association of Serotype of Streptococcus pneumoniae With Risk of Severe and Fatal Outcome

Association of Serotype of Streptococcus pneumoniae With Risk of Severe and Fatal Outcome

BACKGROUND:Invasive pneumococcal disease (IPD) in children may manifest as bacteremia/sepsis, bacteremic pneumonia, or meningitis, with serious outcomes that include hospitalization, neurologic sequelae, or death. The risk of severe or fatal outcome of disease is associated with host-related factors...

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Veröffentlicht in:The Pediatric infectious disease journal 2009-02, Vol.28 (2), p.118-122
Hauptverfasser: Rückinger, Simon, von Kries, Rüdiger, Siedler, Annette, van der Linden, Mark
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Bacterial diseases
Biological and medical sciences
Child
Child, Preschool
Female
Human bacterial diseases
Humans
Infant
Infectious diseases
Male
Medical sciences
Multivariate Analysis
Odds Ratio
Pneumococcal Infections - microbiology
Pneumococcal Infections - mortality
Retrospective Studies
Risk Factors
Serotyping
Staphylococcal infections, streptococcal infections, pneumococcal infections
Streptococcus pneumoniae - classification
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Zusammenfassung:BACKGROUND:Invasive pneumococcal disease (IPD) in children may manifest as bacteremia/sepsis, bacteremic pneumonia, or meningitis, with serious outcomes that include hospitalization, neurologic sequelae, or death. The risk of severe or fatal outcome of disease is associated with host-related factors, such as age or comorbid conditions. Furthermore, there is an ongoing discussion about organism-related factors, such as the pneumococcal serotype. METHODS:Data on 494 children aged
ISSN:0891-3668
1532-0987
DOI:10.1097/INF.0b013e318187e215