Thyroid Function Abnormalities and Cognitive Impairment in Elderly People: Results of the Invecchiare in Chianti Study

OBJECTIVES: To investigate thyroid function testing abnormalities in older persons and to explore the relationship between thyroid dysfunction and cognition. DESIGN: Cross‐sectional. SETTING: Community‐based. PARTICIPANTS: One thousand one hundred seventy‐one men and women aged 23 to 102. MEASUREMEN...

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Veröffentlicht in:	Journal of the American Geriatrics Society (JAGS) 2009-01, Vol.57 (1), p.89-93
Hauptverfasser:	Ceresini, Graziano, Lauretani, Fulvio, Maggio, Marcello, Ceda, Gian Paolo, Morganti, Simonetta, Usberti, Elisa, Chezzi, Carlo, Valcavi, Rita, Bandinelli, Stefania, Guralnik, Jack M., Cappola, Anne R., Valenti, Giorgio, Ferrucci, Luigi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Aged Aged, 80 and over aging Biological and medical sciences cognition Cognition Disorders - complications Cross-Sectional Studies Dementia Female General aspects Geriatrics Humans Hyperthyroidism - blood Hyperthyroidism - complications Hypothyroidism - blood Hypothyroidism - complications Italy Male Medical sciences Middle Aged Miscellaneous Older people Public health. Hygiene Public health. Hygiene-occupational medicine Risk factors Thyroid diseases thyroid function Thyroid Function Tests Young Adult
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Zusammenfassung:	OBJECTIVES: To investigate thyroid function testing abnormalities in older persons and to explore the relationship between thyroid dysfunction and cognition. DESIGN: Cross‐sectional. SETTING: Community‐based. PARTICIPANTS: One thousand one hundred seventy‐one men and women aged 23 to 102. MEASUREMENTS: Thyroid function was evaluated by measuring plasma concentrations of thyrotropin (TSH), free thyroxine (FT4), and free triiodothyronine (FT3). Cognition was evaluated using the Mini‐Mental State Examination (MMSE). Prevalence of overt and subclinical thyroid dysfunction was evaluated in different age groups (
ISSN:	0002-8614 1532-5415 1532-5415
DOI:	10.1111/j.1532-5415.2008.02080.x