Reeling in the bases

Eco R124I is a type I DNA restriction and modification enzyme. The single-molecule magnetic tweezers technique reveals that this sophisticated molecular machine is capable of moving thousands of base pairs of DNA in one binding event.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature structural & molecular biology 2004-09, Vol.11 (9), p.804-806
1. Verfasser:	Dryden, David T F
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biological Microscopy Biomedical and Life Sciences Biotechnology Deoxyribonucleases, Type I Site-Specific - chemistry Deoxyribonucleases, Type I Site-Specific - physiology DNA DNA - chemistry DNA damage DNA Restriction Enzymes - chemistry DNA Restriction Enzymes - physiology Life Sciences Membrane Biology Models, Biological news-and-views Physiological aspects Protein Structure Restriction enzymes, DNA Structure
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Beschreibung
Zusammenfassung:	Eco R124I is a type I DNA restriction and modification enzyme. The single-molecule magnetic tweezers technique reveals that this sophisticated molecular machine is capable of moving thousands of base pairs of DNA in one binding event.
ISSN:	1545-9993 1545-9985
DOI:	10.1038/nsmb0904-804