Glycoprotein Synthesis: An Update

Recent developments in glycoprotein synthesis are discussed. Some synthetic glycoproteins are favored as drug- and gene-delivery systems, particularly when the liver is the target.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical reviews 2009-01, Vol.109 (1), p.131-163
Hauptverfasser:	Gamblin, David P, Scanlan, Eoin M, Davis, Benjamin G
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical research Gene therapy Glycopeptides - biosynthesis Glycopeptides - chemical synthesis Glycopeptides - chemistry Glycoproteins Glycoproteins - biosynthesis Glycoproteins - chemical synthesis Glycoproteins - chemistry Models, Chemical Monosaccharides - chemical synthesis Monosaccharides - chemistry Organic chemistry Pharmacology Polysaccharides - chemical synthesis Polysaccharides - chemistry
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Beschreibung
Zusammenfassung:	Recent developments in glycoprotein synthesis are discussed. Some synthetic glycoproteins are favored as drug- and gene-delivery systems, particularly when the liver is the target.
ISSN:	0009-2665 1520-6890
DOI:	10.1021/cr078291i