How in vitro techniques have increased our understanding of uveal melanoma cellular biology

How in vitro techniques have increased our understanding of uveal melanoma cellular biology

The past decade has seen a rapid increase in powerful in vitro techniques allowing for the specific study of the biologic properties of tumours. In this review we discuss the role of in vitro studies in providing insight into the biologic mechanisms involved in uveal melanoma. We also review the bas...

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Veröffentlicht in:Canadian journal of ophthalmology 2004-06, Vol.39 (4), p.428-432
Hauptverfasser: Marshall, Jean-Claude A., Caissie, Amanda L., Burnier, Miguel N.
Format: Artikel
Sprache:eng
Schlagworte:
Biology
bioluminescence
cell culture
Chemotherapy, Adjuvant
Cytological Techniques
green fluorescent protein
Humans
in vitro
In Vitro Techniques
Melanoma - metabolism
Melanoma - pathology
Melanoma - therapy
Molecular Diagnostic Techniques
review
Tumor Cells, Cultured
uveal melanoma
Uveal Neoplasms - metabolism
Uveal Neoplasms - pathology
Uveal Neoplasms - therapy
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Zusammenfassung:The past decade has seen a rapid increase in powerful in vitro techniques allowing for the specific study of the biologic properties of tumours. In this review we discuss the role of in vitro studies in providing insight into the biologic mechanisms involved in uveal melanoma. We also review the basis of these studies for the development of adjuvant therapies to aid in the treatment of systemic disease in patients with uveal melanoma.
ISSN:0008-4182
1715-3360
DOI:10.1016/S0008-4182(04)80015-2