Cross-relaxation imaging reveals detailed anatomy of white matter fiber tracts in the human brain

Cross-relaxation imaging is a new quantitative MRI modality, which allows mapping of fundamental parameters determining the magnetization transfer (MT) effect in tissues, cross-relaxation rate constant ( k) and bound pool fraction ( f). This study introduces a new time-efficient technique for cross-...

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Veröffentlicht in:	NeuroImage (Orlando, Fla.) Fla.), 2004-09, Vol.23 (1), p.409-424
Hauptverfasser:	Yarnykh, Vasily L., Yuan, Chun
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Axons - pathology Brain - pathology Brain anatomy Brain Mapping - methods Cattle Cross-relaxation Data processing Dominance, Cerebral - physiology Fiber tracts Humans Image Processing, Computer-Assisted - methods Imaging, Three-Dimensional - methods Magnetic Resonance Imaging Magnetization transfer Mathematical Computing Methods Multiple Sclerosis - pathology Nerve Fibers, Myelinated - pathology NMR Nuclear magnetic resonance Pyramidal Tracts - pathology Quantitative MRI Reference Values Theory White matter
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Beschreibung
Zusammenfassung:	Cross-relaxation imaging is a new quantitative MRI modality, which allows mapping of fundamental parameters determining the magnetization transfer (MT) effect in tissues, cross-relaxation rate constant ( k) and bound pool fraction ( f). This study introduces a new time-efficient technique for cross-relaxation imaging, which obtains three-dimensional (3D) whole-brain k and f maps with scan time of
ISSN:	1053-8119 1095-9572
DOI:	10.1016/j.neuroimage.2004.04.029