Characterization of the phrenic nerve course within the epicardial substrate of patients with nonischemic cardiomyopathy and ventricular tachycardia

Background Patients with nonischemic cardiomyopathy and ventricular tachycardia (VT) often have low-voltage areas in the lateral left ventricular (LV) epicardium that serve as the VT substrate. The course of the left phrenic nerve in this region may pose a challenge to successful and safe ablation....

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Veröffentlicht in:	Heart rhythm 2009, Vol.6 (1), p.59-64
Hauptverfasser:	Fan, Roger, MD, Cano, Oscar, MD, Ho, Siew Yen, PhD, FRC Path, FESC, Bala, Rupa, MD, Callans, David J., MD, FHRS, Dixit, Sanjay, MD, FHRS, Garcia, Fermin, MD, Gerstenfeld, Edward P., MD, Hutchinson, Mathew, MD, Lin, David, MD, Riley, Michael, MD, PhD, Marchlinski, Francis E., MD, FHRS
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Body Surface Potential Mapping - methods Cardiomyopathies - complications Cardiomyopathies - physiopathology Cardiomyopathies - surgery Cardiovascular Catheter ablation Catheter Ablation - methods Epicardial Female Follow-Up Studies Humans Intraoperative Complications - prevention & control Male Middle Aged Nonischemic cardiomyopathy Pericardium - innervation Pericardium - surgery Peripheral Nervous System Diseases - prevention & control Phrenic nerve Phrenic Nerve - physiopathology Risk Factors Tachycardia, Ventricular - complications Tachycardia, Ventricular - physiopathology Tachycardia, Ventricular - surgery Ventricular tachycardia Voltage mapping
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Zusammenfassung:	Background Patients with nonischemic cardiomyopathy and ventricular tachycardia (VT) often have low-voltage areas in the lateral left ventricular (LV) epicardium that serve as the VT substrate. The course of the left phrenic nerve in this region may pose a challenge to successful and safe ablation. Objective The purpose of this study was to delineate the left phrenic nerve course in patients with nonischemic cardiomyopathy and suspected epicardial VT and to characterize its relationship with the VT substrate. Methods In 10 patients with nonischemic cardiomyopathy undergoing epicardial VT mapping and ablation, the course of the phrenic nerve was defined by pacing. The extent of epicardial LV low-voltage areas (
ISSN:	1547-5271 1556-3871
DOI:	10.1016/j.hrthm.2008.09.033