Chewing the Fat: Regulating Autophagy in Drosophila

Autophagy is the major cellular process responsible for bulk cytoplasmic degradation. Two reports in this issue of Developmental Cell describe how both PI3 kinase and TOR signaling in Drosophila are critical for controlling autophagy in response to developmental and environmental cues.

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Bibliographische Detailangaben
Veröffentlicht in:	Developmental Cell 2004-08, Vol.7 (2), p.148-150
Hauptverfasser:	Grewal, Savraj S., Saucedo, Leslie J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autophagy Caenorhabditis elegans Cytoplasm - metabolism Drosophila Drosophila melanogaster - metabolism Drosophila melanogaster - physiology Drosophila Proteins - metabolism Gene Expression Regulation, Developmental Insulin - metabolism Models, Biological Phosphatidylinositol 3-Kinases - metabolism Protein Kinases Signal Transduction Time Factors TOR Serine-Threonine Kinases
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Beschreibung
Zusammenfassung:	Autophagy is the major cellular process responsible for bulk cytoplasmic degradation. Two reports in this issue of Developmental Cell describe how both PI3 kinase and TOR signaling in Drosophila are critical for controlling autophagy in response to developmental and environmental cues.
ISSN:	1534-5807 1878-1551
DOI:	10.1016/j.devcel.2004.07.014