MALT lymphoma: from morphology to molecules

Hints that the growth of some lymphomas is stimulated by bacterial antigens and can be controlled by treatment with antibiotics first emerged in the 1970s. Subsequently, a specific type of B-cell lymphoma — mucosa-associated lymphoid tissue (MALT) lymphoma — was identified that is associated with ba...

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Veröffentlicht in:Nature reviews. Cancer 2004-08, Vol.4 (8), p.644-653
Hauptverfasser: Isaacson, Peter G., Du, Ming-Qing
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Du, Ming-Qing
description Hints that the growth of some lymphomas is stimulated by bacterial antigens and can be controlled by treatment with antibiotics first emerged in the 1970s. Subsequently, a specific type of B-cell lymphoma — mucosa-associated lymphoid tissue (MALT) lymphoma — was identified that is associated with bacterial infection and auto-antigen stimulation. This article chronicles the clinical, immunological and molecular developments in our knowledge of MALT lymphoma and the factors that contribute to its pathogenesis.
doi_str_mv 10.1038/nrc1409
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subjects Autoantigens
Biomedical and Life Sciences
Biomedicine
Cancer Research
Care and treatment
Diagnosis
Helicobacter Infections - complications
Humans
Immune response
Lymphoma, B-Cell, Marginal Zone - genetics
Lymphoma, B-Cell, Marginal Zone - immunology
Lymphoma, B-Cell, Marginal Zone - pathology
MALT lymphoma
Physiological aspects
Prevention
Risk Factors
timeline
Translocation, Genetic
title MALT lymphoma: from morphology to molecules
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