Cathepsin G increases MMP expression in normal human fibroblasts through fibronectin fragmentation, and induces the conversion of proMMP-1 to active MMP-1

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Veröffentlicht in:	Journal of dermatological science 2009-02, Vol.53 (2), p.150-152
Hauptverfasser:	Son, Eui Dong, Kim, Hyaekyoung, Choi, Hyunjung, Lee, So Hee, Lee, Jin Young, Kim, Sujung, Closs, B, Lee, Sera, Chung, Jin Ho, Hwang, Jae Sung
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Aged Aging Buttocks Cathepsin G Cathepsins - antagonists & inhibitors Cathepsins - metabolism Cells, Cultured Dermatology Enzyme Activation Enzyme Precursors - metabolism Extracellular matrix Female Fibroblasts - drug effects Fibroblasts - enzymology Fibroblasts - radiation effects Fibronectin Fibronectin fragments Fibronectins - metabolism Humans Male Matrix Metalloproteinase 1 - genetics Matrix Metalloproteinase 1 - metabolism Matrix Metalloproteinase 2 - metabolism Middle Aged Peptide Fragments - metabolism RNA, Messenger - metabolism Serine Endopeptidases - metabolism Serine Proteinase Inhibitors - pharmacology Skin - cytology Skin - drug effects Skin - enzymology Skin - radiation effects Skin aging Ultraviolet Rays
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