Specificity of a high-sensitivity cardiac troponin I assay using single-molecule-counting technology

Specificity of a high-sensitivity cardiac troponin I assay using single-molecule-counting technology

To test capture antibody NSB, we obtained 8 additional serum samples from healthy blood bank donors (4 male, 4 female, mean age 25.5 years, range 22-30 years). Analyte NSB events were tested with standard curves and linear regression analysis of cTnI standard (NIST) and nonspecific skeletal troponin...

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Veröffentlicht in:Clinical chemistry (Baltimore, Md.) Md.), 2009-01, Vol.55 (1), p.196-198
Hauptverfasser: Wu, Alan H B, Agee, Sara J, Lu, Quynh Anh, Todd, John, Jaffe, Allan S
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Blood banks
Female
Fluorescence
Heart attacks
Humans
Immunoassay
Male
Middle Aged
Prognosis
Reference Values
Regression analysis
Sensitivity and Specificity
Troponin I - blood
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Zusammenfassung:To test capture antibody NSB, we obtained 8 additional serum samples from healthy blood bank donors (4 male, 4 female, mean age 25.5 years, range 22-30 years). Analyte NSB events were tested with standard curves and linear regression analysis of cTnI standard (NIST) and nonspecific skeletal troponin (Hytest) assayed over 0.1-100 ng/L.
ISSN:0009-9147
1530-8561
DOI:10.1373/clinchem.2008.108837