Tissue trauma after vaginal hysterectomy and colporrhaphy versus abdominal hysterectomy: A randomised controlled study

Objective: As the magnitude of tissue trauma can be detected by measuring the blood levels of acute phase reactants, we aimed to evaluate tissue trauma markers after abdominal hysterectomy (AH) and vaginal hysterectomy (VH). We hypothesised that VH will be associated with a reduced increase in the level of acute phase reactants than AH. Methods: Thirty women out of 92 patients scheduled for hysterectomies between June 2002 and June 2003 were randomised into two equal groups (n = 15) of VH and AH. Their levels of C‐reactive protein (CRP), α1‐antitrypsin (α1‐AT) and myoglobin (M) were analysed preoperatively and on the second, fourth and sixth days. Results: In both methods of hysterectomy, the operating time (85.3 ± 6.57 min in the VH group vs 69 ± 7.54 min in the AH group, P