Insulin-like growth factor-I gene polymorphism and risk of heart failure (the Rotterdam Study)

We studied 4,963 participants of the population-based Rotterdam Study and found that a genetically determined chronic exposure to low insulin-like growth factor-I (IGF-I) levels is associated with an increased risk for heart failure in elderly patients.

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Veröffentlicht in:The American journal of cardiology 2004-08, Vol.94 (3), p.384-386
Hauptverfasser: Bleumink, Gysèle S, Rietveld, Ingrid, Janssen, Joop A.M..J.L, van Rossum, Elisabeth F.C, Deckers, Jaap W, Hofman, Albert, Witteman, Jacqueline C.M, van Duijn, Cornelia M, Stricker, Bruno H.Ch
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Sprache:eng
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Zusammenfassung:We studied 4,963 participants of the population-based Rotterdam Study and found that a genetically determined chronic exposure to low insulin-like growth factor-I (IGF-I) levels is associated with an increased risk for heart failure in elderly patients.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2004.04.044