Detection of bcl-2 rearrangement in mucosa-associated lymphoid tissue lymphomas from patients with hepatitis C virus infection

It has been shown that t(14;18)(q32;q21) involving fusion of IGH with MALT1 occurs frequently in mucosa-associated lymphoid tissue (MALT) lymphomas. Results of the present study indicate that the classical form of t(14;18)(q32;q21) involving fusion of IGH with bcl-2 can be detectable in a subset of...

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Veröffentlicht in:	Haematologica (Roma) 2004-07, Vol.89 (7), p.873-874
Hauptverfasser:	Libra, M, De Re, V, Gloghini, A, Gasparotto, D, Gragnani, L, Navolanic, PM, De Vita, S, Mazzarino, MC, Zignego, AL, Carbone, A, Boiocchi, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Female Gene Rearrangement, B-Lymphocyte Genes, bcl-2 - genetics Hepatitis C - complications Hepatitis C - genetics Humans Lymphoma, B-Cell, Marginal Zone - genetics Lymphoma, B-Cell, Marginal Zone - virology Male Middle Aged
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Zusammenfassung:	It has been shown that t(14;18)(q32;q21) involving fusion of IGH with MALT1 occurs frequently in mucosa-associated lymphoid tissue (MALT) lymphomas. Results of the present study indicate that the classical form of t(14;18)(q32;q21) involving fusion of IGH with bcl-2 can be detectable in a subset of MALT lymphomas in patients with hepatitis C virus (HCV) infection.
ISSN:	0390-6078 1592-8721