BCG Granulomatosis in Adult Mice of Different Strains with a History of Intrauterine Hypoxia
Specific features of the formation and spontaneous regression of BCG granulomas, depending on mouse genotype and history of intrauterine hypoxia, were detected in 2-month-old male CBA and C57Bl/6 mice. The numerical density of granulomas, their size and (partially) cell composition varied. There are...
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| Veröffentlicht in: | Bulletin of experimental biology and medicine 2008-12, Vol.146 (6), p.842-844 |
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| container_title | Bulletin of experimental biology and medicine |
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| creator | Nadeev, A. P Kuznetsova, I. V Shkurupiy, V. A |
| description | Specific features of the formation and spontaneous regression of BCG granulomas, depending on mouse genotype and history of intrauterine hypoxia, were detected in 2-month-old male CBA and C57Bl/6 mice. The numerical density of granulomas, their size and (partially) cell composition varied. There are good grounds to assume that the number of BCG granulomas in the liver, irrespective of the experimental conditions and animal strains, decreases after elimination of M. tuberculosis persisting in granuloma phagocytes and subsequent migration of cells constituting the granuloma. |
| doi_str_mv | 10.1007/s10517-009-0406-5 |
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There are good grounds to assume that the number of BCG granulomas in the liver, irrespective of the experimental conditions and animal strains, decreases after elimination of M. tuberculosis persisting in granuloma phagocytes and subsequent migration of cells constituting the granuloma.</description><identifier>ISSN: 0007-4888</identifier><identifier>EISSN: 1573-8221</identifier><identifier>DOI: 10.1007/s10517-009-0406-5</identifier><identifier>PMID: 19513401</identifier><identifier>CODEN: BEXBAN</identifier><language>eng</language><publisher>Boston: Boston : Springer US</publisher><subject>Animals ; BCG granulomatosis ; BCG Vaccine - adverse effects ; Biomedical and Life Sciences ; Biomedicine ; Cell Biology ; Female ; Fetal Hypoxia - physiopathology ; genotype ; Granuloma - etiology ; Granuloma - pathology ; Internal Medicine ; intrauterine hypoxia ; Laboratory Medicine ; liver ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Inbred CBA ; Morphology and Pathomorphology ; Mycobacterium ; Pathology ; postpartum period</subject><ispartof>Bulletin of experimental biology and medicine, 2008-12, Vol.146 (6), p.842-844</ispartof><rights>Springer Science+Business Media, Inc. 2008</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c376t-dcd47f16de3a3e853b785175985e2c9c41908860c49473774777dca5f5c376133</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10517-009-0406-5$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10517-009-0406-5$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51298</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19513401$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nadeev, A. P</creatorcontrib><creatorcontrib>Kuznetsova, I. V</creatorcontrib><creatorcontrib>Shkurupiy, V. A</creatorcontrib><title>BCG Granulomatosis in Adult Mice of Different Strains with a History of Intrauterine Hypoxia</title><title>Bulletin of experimental biology and medicine</title><addtitle>Bull Exp Biol Med</addtitle><addtitle>Bull Exp Biol Med</addtitle><description>Specific features of the formation and spontaneous regression of BCG granulomas, depending on mouse genotype and history of intrauterine hypoxia, were detected in 2-month-old male CBA and C57Bl/6 mice. The numerical density of granulomas, their size and (partially) cell composition varied. There are good grounds to assume that the number of BCG granulomas in the liver, irrespective of the experimental conditions and animal strains, decreases after elimination of M. tuberculosis persisting in granuloma phagocytes and subsequent migration of cells constituting the granuloma.</description><subject>Animals</subject><subject>BCG granulomatosis</subject><subject>BCG Vaccine - adverse effects</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cell Biology</subject><subject>Female</subject><subject>Fetal Hypoxia - physiopathology</subject><subject>genotype</subject><subject>Granuloma - etiology</subject><subject>Granuloma - pathology</subject><subject>Internal Medicine</subject><subject>intrauterine hypoxia</subject><subject>Laboratory Medicine</subject><subject>liver</subject><subject>Male</subject><subject>Mice</subject><subject>Mice, Inbred C57BL</subject><subject>Mice, Inbred CBA</subject><subject>Morphology and Pathomorphology</subject><subject>Mycobacterium</subject><subject>Pathology</subject><subject>postpartum period</subject><issn>0007-4888</issn><issn>1573-8221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkU9v1DAQxS0EokvhA3ABiwO3tB7_97EssFupqIfSG5LlJk5xlbUXOxHst6-jrFSJA8xlNJrfe6PRQ-gtkDMgRJ0XIAJUQ4hpCCeyEc_QCoRijaYUnqMVqVDDtdYn6FUpD_NIJLxEJ2AEME5ghX58Wm_wJrs4DWnnxlRCwSHii24aRvwttB6nHn8Ofe-zjyO-GbMLseDfYfyJHd6GMqZ8mJnLWFfT6HOIHm8P-_QnuNfoRe-G4t8c-ym6_frl-3rbXF1vLtcXV03LlBybru246kF2njnmtWB3Ste_hNHC09a0HAzRWpKWG66YUlwp1bVO9GLWA2On6OPiu8_p1-TLaHehtH4YXPRpKlZKBdwA_BekRApaq4If_gIf0pRjfcLSelAZA7xCsEBtTqVk39t9DjuXDxaInQOyS0C2BmTngKyomndH4-lu57snxTGRCtAFKHUV731-uvwv1_eLqHfJuvscir29odWNgGRAtWaPyDCh3Q</recordid><startdate>20081201</startdate><enddate>20081201</enddate><creator>Nadeev, A. 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P ; Kuznetsova, I. V ; Shkurupiy, V. A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c376t-dcd47f16de3a3e853b785175985e2c9c41908860c49473774777dca5f5c376133</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Animals</topic><topic>BCG granulomatosis</topic><topic>BCG Vaccine - adverse effects</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Cell Biology</topic><topic>Female</topic><topic>Fetal Hypoxia - physiopathology</topic><topic>genotype</topic><topic>Granuloma - etiology</topic><topic>Granuloma - pathology</topic><topic>Internal Medicine</topic><topic>intrauterine hypoxia</topic><topic>Laboratory Medicine</topic><topic>liver</topic><topic>Male</topic><topic>Mice</topic><topic>Mice, Inbred C57BL</topic><topic>Mice, Inbred CBA</topic><topic>Morphology and Pathomorphology</topic><topic>Mycobacterium</topic><topic>Pathology</topic><topic>postpartum period</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nadeev, A. 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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Animals BCG granulomatosis BCG Vaccine - adverse effects Biomedical and Life Sciences Biomedicine Cell Biology Female Fetal Hypoxia - physiopathology genotype Granuloma - etiology Granuloma - pathology Internal Medicine intrauterine hypoxia Laboratory Medicine liver Male Mice Mice, Inbred C57BL Mice, Inbred CBA Morphology and Pathomorphology Mycobacterium Pathology postpartum period |
| title | BCG Granulomatosis in Adult Mice of Different Strains with a History of Intrauterine Hypoxia |
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