Multipotent Mesenchymal Stromal Cells of Autologous Bone Marrow Stimulate Neoangiogenesis, Restore Microcirculation, and Promote Healing of Indolent Ulcers of the Stomach

The effects of precultured multipotent mesenchymal stromal cells from autologous bone marrow on microcirculation and regeneration of experimental indolent stomach ulcer were studied in experiments on rats. It was demonstrated that precultured multipotent mesenchymal stromal bone marrow cells deliver...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2008-10, Vol.146 (4), p.512-516
Hauptverfasser: Askarov, M. B., Onischenko, N. A.
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Onischenko, N. A.
description The effects of precultured multipotent mesenchymal stromal cells from autologous bone marrow on microcirculation and regeneration of experimental indolent stomach ulcer were studied in experiments on rats. It was demonstrated that precultured multipotent mesenchymal stromal bone marrow cells delivered to the zone of chronic gastric ulcer stimulate neoangiogemesis, improve microcirculation in the gastric mucosa, and promote ulcer healing.
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subjects Animals
Biomedical and Life Sciences
Biomedicine
Bone Marrow Cells - cytology
Bone Marrow Cells - physiology
Cell Biology
Cell- and Tissue-Based Therapy
Internal Medicine
Laboratory Medicine
Male
Mesenchymal Stem Cells - cytology
Mesenchymal Stem Cells - physiology
Microcirculation - physiology
Neovascularization, Physiologic - physiology
Pathology
Rats
Rats, Wistar
Stomach Ulcer - therapy
Stromal Cells - cytology
Stromal Cells - physiology
Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
Wound Healing - physiology
title Multipotent Mesenchymal Stromal Cells of Autologous Bone Marrow Stimulate Neoangiogenesis, Restore Microcirculation, and Promote Healing of Indolent Ulcers of the Stomach
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