Gonadotropin treatment of an azoospermic patient with a Y-chromosome microdeletion
To report on the treatment with recombinant FSH of an azoospermic normogonadotropic patient with a Y-chromosome microdeletion. Case report. An assisted reproduction center. A 32-year-old patient with azoospermia. Histological testicular biopsy, Y-chromosome screening, FSH treatment, and intracytopla...
Gespeichert in:
| Veröffentlicht in: | Fertility and sterility 2004-07, Vol.82 (1), p.218-219 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 219 |
|---|---|
| container_issue | 1 |
| container_start_page | 218 |
| container_title | Fertility and sterility |
| container_volume | 82 |
| creator | Selman, Helmy A Cipollone, Giovanni Stuppia, Liborio De Santo, Mariella Sterzik, Karl El-Danasouri, Imam |
| description | To report on the treatment with recombinant FSH of an azoospermic normogonadotropic patient with a Y-chromosome microdeletion.
Case report.
An assisted reproduction center.
A 32-year-old patient with azoospermia.
Histological testicular biopsy, Y-chromosome screening, FSH treatment, and intracytoplasmic sperm injection.
Fertilization, embryo development, pregnancy, and delivery.
After 6 months of treatment with gonadotropins, a small number of spermatozoa were found in the patient's ejaculate and used for IVF, resulting in a successful twin pregnancy and the delivery of two healthy girls.
In this study, treatment with gonadotropins promoted the spermatogenesis process and led to the production of spermatozoa in a normogonadotropic azoospermic patient. |
| doi_str_mv | 10.1016/j.fertnstert.2003.11.055 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_66677899</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0015028204005588</els_id><sourcerecordid>66677899</sourcerecordid><originalsourceid>FETCH-LOGICAL-c450t-c5be14dbf278b4757b3c28f73c755a964bac60565270ee0cdf3a8762faa0b7a43</originalsourceid><addsrcrecordid>eNqFkE1P3DAQQK2KCraUv1D5Um5JbSe2k2OLClRCQkLtoSdr4oyFV0mc2l4Q_fX1aleCWy8zh3nz9QihnNWccfVlWzuMeUm5xFow1tSc10zKd2TDpVSVVLI5IRvGuKyY6MQZ-ZDSljGmuBan5IxL0egyaEMebsICY8gxrH6hOSLkGZdMg6OwUPgbQloxzt7SFbLfV559fqRAf1f2MYY5pDAjLfUYRpww-7B8JO8dTAkvjvmc_Lr-_vPqtrq7v_lx9fWusq1kubJyQN6OgxO6G1ot9dBY0TndWC0l9KodwCpWPhGaITI7ugY6rYQDYIOGtjknl4e5awx_dpiymX2yOE2wYNglo5TSuuv7AnYHsByZUkRn1uhniC-GM7P3abbm1afZ-zScm-KztH467tgNM46vjUeBBfh8BCBZmFyExfr0hutl2_e8cN8OHBYjTx6jSbbotDj6iDabMfj_X_MPxtGa2Q</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>66677899</pqid></control><display><type>article</type><title>Gonadotropin treatment of an azoospermic patient with a Y-chromosome microdeletion</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Selman, Helmy A ; Cipollone, Giovanni ; Stuppia, Liborio ; De Santo, Mariella ; Sterzik, Karl ; El-Danasouri, Imam</creator><creatorcontrib>Selman, Helmy A ; Cipollone, Giovanni ; Stuppia, Liborio ; De Santo, Mariella ; Sterzik, Karl ; El-Danasouri, Imam</creatorcontrib><description>To report on the treatment with recombinant FSH of an azoospermic normogonadotropic patient with a Y-chromosome microdeletion.
Case report.
An assisted reproduction center.
A 32-year-old patient with azoospermia.
Histological testicular biopsy, Y-chromosome screening, FSH treatment, and intracytoplasmic sperm injection.
Fertilization, embryo development, pregnancy, and delivery.
After 6 months of treatment with gonadotropins, a small number of spermatozoa were found in the patient's ejaculate and used for IVF, resulting in a successful twin pregnancy and the delivery of two healthy girls.
In this study, treatment with gonadotropins promoted the spermatogenesis process and led to the production of spermatozoa in a normogonadotropic azoospermic patient.</description><identifier>ISSN: 0015-0282</identifier><identifier>EISSN: 1556-5653</identifier><identifier>DOI: 10.1016/j.fertnstert.2003.11.055</identifier><identifier>PMID: 15237016</identifier><identifier>CODEN: FESTAS</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Azoospermia ; Biological and medical sciences ; Chromosomes, Human, Y ; Female ; Fertilization in Vitro ; Follicle Stimulating Hormone - therapeutic use ; Gene Deletion ; Gynecology. Andrology. Obstetrics ; Hormones - therapeutic use ; human chorionic gonadotropin ; human recombinant FSH ; Humans ; Infant, Newborn ; intracytoplasmic sperm injection ; Male ; Male genital diseases ; Medical sciences ; Non tumoral diseases ; Oligospermia - drug therapy ; Oligospermia - genetics ; Oligospermia - physiopathology ; Pregnancy ; Pregnancy, Multiple ; Sperm Injections, Intracytoplasmic ; Spermatogenesis - drug effects ; Twins ; Y-chromosome screening</subject><ispartof>Fertility and sterility, 2004-07, Vol.82 (1), p.218-219</ispartof><rights>2004 American Society for Reproductive Medicine</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c450t-c5be14dbf278b4757b3c28f73c755a964bac60565270ee0cdf3a8762faa0b7a43</citedby><cites>FETCH-LOGICAL-c450t-c5be14dbf278b4757b3c28f73c755a964bac60565270ee0cdf3a8762faa0b7a43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0015028204005588$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15954991$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15237016$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Selman, Helmy A</creatorcontrib><creatorcontrib>Cipollone, Giovanni</creatorcontrib><creatorcontrib>Stuppia, Liborio</creatorcontrib><creatorcontrib>De Santo, Mariella</creatorcontrib><creatorcontrib>Sterzik, Karl</creatorcontrib><creatorcontrib>El-Danasouri, Imam</creatorcontrib><title>Gonadotropin treatment of an azoospermic patient with a Y-chromosome microdeletion</title><title>Fertility and sterility</title><addtitle>Fertil Steril</addtitle><description>To report on the treatment with recombinant FSH of an azoospermic normogonadotropic patient with a Y-chromosome microdeletion.
Case report.
An assisted reproduction center.
A 32-year-old patient with azoospermia.
Histological testicular biopsy, Y-chromosome screening, FSH treatment, and intracytoplasmic sperm injection.
Fertilization, embryo development, pregnancy, and delivery.
After 6 months of treatment with gonadotropins, a small number of spermatozoa were found in the patient's ejaculate and used for IVF, resulting in a successful twin pregnancy and the delivery of two healthy girls.
In this study, treatment with gonadotropins promoted the spermatogenesis process and led to the production of spermatozoa in a normogonadotropic azoospermic patient.</description><subject>Adult</subject><subject>Azoospermia</subject><subject>Biological and medical sciences</subject><subject>Chromosomes, Human, Y</subject><subject>Female</subject><subject>Fertilization in Vitro</subject><subject>Follicle Stimulating Hormone - therapeutic use</subject><subject>Gene Deletion</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Hormones - therapeutic use</subject><subject>human chorionic gonadotropin</subject><subject>human recombinant FSH</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>intracytoplasmic sperm injection</subject><subject>Male</subject><subject>Male genital diseases</subject><subject>Medical sciences</subject><subject>Non tumoral diseases</subject><subject>Oligospermia - drug therapy</subject><subject>Oligospermia - genetics</subject><subject>Oligospermia - physiopathology</subject><subject>Pregnancy</subject><subject>Pregnancy, Multiple</subject><subject>Sperm Injections, Intracytoplasmic</subject><subject>Spermatogenesis - drug effects</subject><subject>Twins</subject><subject>Y-chromosome screening</subject><issn>0015-0282</issn><issn>1556-5653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1P3DAQQK2KCraUv1D5Um5JbSe2k2OLClRCQkLtoSdr4oyFV0mc2l4Q_fX1aleCWy8zh3nz9QihnNWccfVlWzuMeUm5xFow1tSc10zKd2TDpVSVVLI5IRvGuKyY6MQZ-ZDSljGmuBan5IxL0egyaEMebsICY8gxrH6hOSLkGZdMg6OwUPgbQloxzt7SFbLfV559fqRAf1f2MYY5pDAjLfUYRpww-7B8JO8dTAkvjvmc_Lr-_vPqtrq7v_lx9fWusq1kubJyQN6OgxO6G1ot9dBY0TndWC0l9KodwCpWPhGaITI7ugY6rYQDYIOGtjknl4e5awx_dpiymX2yOE2wYNglo5TSuuv7AnYHsByZUkRn1uhniC-GM7P3abbm1afZ-zScm-KztH467tgNM46vjUeBBfh8BCBZmFyExfr0hutl2_e8cN8OHBYjTx6jSbbotDj6iDabMfj_X_MPxtGa2Q</recordid><startdate>20040701</startdate><enddate>20040701</enddate><creator>Selman, Helmy A</creator><creator>Cipollone, Giovanni</creator><creator>Stuppia, Liborio</creator><creator>De Santo, Mariella</creator><creator>Sterzik, Karl</creator><creator>El-Danasouri, Imam</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040701</creationdate><title>Gonadotropin treatment of an azoospermic patient with a Y-chromosome microdeletion</title><author>Selman, Helmy A ; Cipollone, Giovanni ; Stuppia, Liborio ; De Santo, Mariella ; Sterzik, Karl ; El-Danasouri, Imam</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c450t-c5be14dbf278b4757b3c28f73c755a964bac60565270ee0cdf3a8762faa0b7a43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adult</topic><topic>Azoospermia</topic><topic>Biological and medical sciences</topic><topic>Chromosomes, Human, Y</topic><topic>Female</topic><topic>Fertilization in Vitro</topic><topic>Follicle Stimulating Hormone - therapeutic use</topic><topic>Gene Deletion</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Hormones - therapeutic use</topic><topic>human chorionic gonadotropin</topic><topic>human recombinant FSH</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>intracytoplasmic sperm injection</topic><topic>Male</topic><topic>Male genital diseases</topic><topic>Medical sciences</topic><topic>Non tumoral diseases</topic><topic>Oligospermia - drug therapy</topic><topic>Oligospermia - genetics</topic><topic>Oligospermia - physiopathology</topic><topic>Pregnancy</topic><topic>Pregnancy, Multiple</topic><topic>Sperm Injections, Intracytoplasmic</topic><topic>Spermatogenesis - drug effects</topic><topic>Twins</topic><topic>Y-chromosome screening</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Selman, Helmy A</creatorcontrib><creatorcontrib>Cipollone, Giovanni</creatorcontrib><creatorcontrib>Stuppia, Liborio</creatorcontrib><creatorcontrib>De Santo, Mariella</creatorcontrib><creatorcontrib>Sterzik, Karl</creatorcontrib><creatorcontrib>El-Danasouri, Imam</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fertility and sterility</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Selman, Helmy A</au><au>Cipollone, Giovanni</au><au>Stuppia, Liborio</au><au>De Santo, Mariella</au><au>Sterzik, Karl</au><au>El-Danasouri, Imam</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Gonadotropin treatment of an azoospermic patient with a Y-chromosome microdeletion</atitle><jtitle>Fertility and sterility</jtitle><addtitle>Fertil Steril</addtitle><date>2004-07-01</date><risdate>2004</risdate><volume>82</volume><issue>1</issue><spage>218</spage><epage>219</epage><pages>218-219</pages><issn>0015-0282</issn><eissn>1556-5653</eissn><coden>FESTAS</coden><abstract>To report on the treatment with recombinant FSH of an azoospermic normogonadotropic patient with a Y-chromosome microdeletion.
Case report.
An assisted reproduction center.
A 32-year-old patient with azoospermia.
Histological testicular biopsy, Y-chromosome screening, FSH treatment, and intracytoplasmic sperm injection.
Fertilization, embryo development, pregnancy, and delivery.
After 6 months of treatment with gonadotropins, a small number of spermatozoa were found in the patient's ejaculate and used for IVF, resulting in a successful twin pregnancy and the delivery of two healthy girls.
In this study, treatment with gonadotropins promoted the spermatogenesis process and led to the production of spermatozoa in a normogonadotropic azoospermic patient.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>15237016</pmid><doi>10.1016/j.fertnstert.2003.11.055</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0015-0282 |
| ispartof | Fertility and sterility, 2004-07, Vol.82 (1), p.218-219 |
| issn | 0015-0282 1556-5653 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_66677899 |
| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adult Azoospermia Biological and medical sciences Chromosomes, Human, Y Female Fertilization in Vitro Follicle Stimulating Hormone - therapeutic use Gene Deletion Gynecology. Andrology. Obstetrics Hormones - therapeutic use human chorionic gonadotropin human recombinant FSH Humans Infant, Newborn intracytoplasmic sperm injection Male Male genital diseases Medical sciences Non tumoral diseases Oligospermia - drug therapy Oligospermia - genetics Oligospermia - physiopathology Pregnancy Pregnancy, Multiple Sperm Injections, Intracytoplasmic Spermatogenesis - drug effects Twins Y-chromosome screening |
| title | Gonadotropin treatment of an azoospermic patient with a Y-chromosome microdeletion |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T08%3A35%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Gonadotropin%20treatment%20of%20an%20azoospermic%20patient%20with%20a%20Y-chromosome%20microdeletion&rft.jtitle=Fertility%20and%20sterility&rft.au=Selman,%20Helmy%20A&rft.date=2004-07-01&rft.volume=82&rft.issue=1&rft.spage=218&rft.epage=219&rft.pages=218-219&rft.issn=0015-0282&rft.eissn=1556-5653&rft.coden=FESTAS&rft_id=info:doi/10.1016/j.fertnstert.2003.11.055&rft_dat=%3Cproquest_cross%3E66677899%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=66677899&rft_id=info:pmid/15237016&rft_els_id=S0015028204005588&rfr_iscdi=true |