Nataxazole, a New Benzoxazole Derivative with Antitumor Activity Produced by Streptomyces sp. Tü 6176
The new benzoxazole derivative nataxazole was isolated from Streptomyces sp. (strain Tü 6176). Nataxazole is related in structure to the potent antitumor compounds UK-1 and AJI9561 and showed similar strong growth inhibitory activity against various human tumor cell lines.
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| Veröffentlicht in: | Journal of antibiotics 2008-11, Vol.61 (11), p.683-686 |
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| container_end_page | 686 |
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| container_issue | 11 |
| container_start_page | 683 |
| container_title | Journal of antibiotics |
| container_volume | 61 |
| creator | Sommer, Patricia S M Almeida, Rosemary C Schneider, Kathrin Beil, Winfried Süssmuth, Roderich D Fiedler, Hans-Peter |
| description | The new benzoxazole derivative nataxazole was isolated from
Streptomyces
sp. (strain Tü 6176). Nataxazole is related in structure to the potent antitumor compounds UK-1 and AJI9561 and showed similar strong growth inhibitory activity against various human tumor cell lines. |
| doi_str_mv | 10.1038/ja.2008.97 |
| format | Article |
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Streptomyces
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| fulltext | fulltext |
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| ispartof | Journal of antibiotics, 2008-11, Vol.61 (11), p.683-686 |
| issn | 0021-8820 1881-1469 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Bacteriology Benzoxazoles - chemistry Benzoxazoles - isolation & purification Benzoxazoles - pharmacology Biomedical and Life Sciences Bioorganic Chemistry Cell Line, Tumor Humans Life Sciences Medicinal Chemistry Microbiology Molecular Structure Organic Chemistry Streptomyces - chemistry Streptomyces - metabolism |
| title | Nataxazole, a New Benzoxazole Derivative with Antitumor Activity Produced by Streptomyces sp. Tü 6176 |
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