Bone mass density and associated factors in cystic fibrosis patients of young age

Bone mass density and associated factors in cystic fibrosis patients of young age

Aim:  To investigate bone mineral status in young cystic fibrosis (CF) patients and determine risk factors related with the development of low bone mineral density (BMD). Methods:  We determined, in 81 patients with CF, 4 to 23‐years‐old, BMD as well as factors, which are thought to play a role in t...

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Veröffentlicht in:Journal of paediatrics and child health 2008-12, Vol.44 (12), p.681-685
Hauptverfasser: Douros, Konstantinos, Loukou, Ioanna, Nicolaidou, Polyxeni, Tzonou, Anastasia, Doudounakis, Stavros
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Bone density
Bone Density - physiology
bone mineral density
Child
Child, Preschool
Cystic fibrosis
Cystic Fibrosis - physiopathology
Female
Gender
Hospitals, Pediatric
Humans
Male
Pediatrics
Risk Factors
Surveys and Questionnaires
United States
Vitamin D
Vitamin D Deficiency
Young Adult
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Zusammenfassung:Aim:  To investigate bone mineral status in young cystic fibrosis (CF) patients and determine risk factors related with the development of low bone mineral density (BMD). Methods:  We determined, in 81 patients with CF, 4 to 23‐years‐old, BMD as well as factors, which are thought to play a role in the development of reduced BMD. Results:  BMD Z‐score was between −1 and −2.5 in 27 (33%) and lower than −2.5 in 9 (11%). Means of BMD Z‐score were lower than the expected value of 0 in the three groups of children, adolescents and young adults (P = 0.004; P 
ISSN:1034-4810
1440-1754
DOI:10.1111/j.1440-1754.2008.01406.x