Two new ecdysteroids from Serratula wolffii
11alpha-Hydroxypoststerone (1) and herkesterone (2), two new natural ecdysteroids, were isolated from the herb Serratula wolffii. The former compound is the first 11-hydroxylated C21 ecdysteroid, while the latter is a new ecdysteroid with a 7,9(11)-dien-6-one chromophore. Their structures were deter...
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Veröffentlicht in: | Journal of natural products (Washington, D.C.) D.C.), 2004-06, Vol.67 (6), p.1070-1072 |
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creator | Hunyadi, A Toth, G Simon, A Mak, M Kele, Z Mathe, I Bathori, M |
description | 11alpha-Hydroxypoststerone (1) and herkesterone (2), two new natural ecdysteroids, were isolated from the herb Serratula wolffii. The former compound is the first 11-hydroxylated C21 ecdysteroid, while the latter is a new ecdysteroid with a 7,9(11)-dien-6-one chromophore. Their structures were determined using a combination of spectroscopic techniques. |
doi_str_mv | 10.1021/np030544p |
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The former compound is the first 11-hydroxylated C21 ecdysteroid, while the latter is a new ecdysteroid with a 7,9(11)-dien-6-one chromophore. Their structures were determined using a combination of spectroscopic techniques.</description><identifier>ISSN: 0163-3864</identifier><identifier>EISSN: 1520-6025</identifier><identifier>DOI: 10.1021/np030544p</identifier><identifier>PMID: 15217300</identifier><identifier>CODEN: JNPRDF</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Analytical, structural and metabolic biochemistry ; Asteraceae - chemistry ; Biological and medical sciences ; Ecdysteroids - chemistry ; Ecdysteroids - isolation & purification ; Ecdysteroids - pharmacology ; Fundamental and applied biological sciences. Psychology ; Hungary ; Molecular Structure ; Nuclear Magnetic Resonance, Biomolecular ; Other biological molecules ; Terpenes, steroids. 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Nat. Prod</addtitle><description>11alpha-Hydroxypoststerone (1) and herkesterone (2), two new natural ecdysteroids, were isolated from the herb Serratula wolffii. The former compound is the first 11-hydroxylated C21 ecdysteroid, while the latter is a new ecdysteroid with a 7,9(11)-dien-6-one chromophore. Their structures were determined using a combination of spectroscopic techniques.</description><subject>Analytical, structural and metabolic biochemistry</subject><subject>Asteraceae - chemistry</subject><subject>Biological and medical sciences</subject><subject>Ecdysteroids - chemistry</subject><subject>Ecdysteroids - isolation & purification</subject><subject>Ecdysteroids - pharmacology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hungary</subject><subject>Molecular Structure</subject><subject>Nuclear Magnetic Resonance, Biomolecular</subject><subject>Other biological molecules</subject><subject>Terpenes, steroids. 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Psychology</topic><topic>Hungary</topic><topic>Molecular Structure</topic><topic>Nuclear Magnetic Resonance, Biomolecular</topic><topic>Other biological molecules</topic><topic>Terpenes, steroids. Hormones</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hunyadi, A</creatorcontrib><creatorcontrib>Toth, G</creatorcontrib><creatorcontrib>Simon, A</creatorcontrib><creatorcontrib>Mak, M</creatorcontrib><creatorcontrib>Kele, Z</creatorcontrib><creatorcontrib>Mathe, I</creatorcontrib><creatorcontrib>Bathori, M</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of natural products (Washington, D.C.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hunyadi, A</au><au>Toth, G</au><au>Simon, A</au><au>Mak, M</au><au>Kele, Z</au><au>Mathe, I</au><au>Bathori, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Two new ecdysteroids from Serratula wolffii</atitle><jtitle>Journal of natural products (Washington, D.C.)</jtitle><addtitle>J. Nat. Prod</addtitle><date>2004-06-01</date><risdate>2004</risdate><volume>67</volume><issue>6</issue><spage>1070</spage><epage>1072</epage><pages>1070-1072</pages><issn>0163-3864</issn><eissn>1520-6025</eissn><coden>JNPRDF</coden><abstract>11alpha-Hydroxypoststerone (1) and herkesterone (2), two new natural ecdysteroids, were isolated from the herb Serratula wolffii. The former compound is the first 11-hydroxylated C21 ecdysteroid, while the latter is a new ecdysteroid with a 7,9(11)-dien-6-one chromophore. Their structures were determined using a combination of spectroscopic techniques.</abstract><cop>Washington, DC</cop><cop>Glendale, AZ</cop><pub>American Chemical Society</pub><pmid>15217300</pmid><doi>10.1021/np030544p</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Analytical, structural and metabolic biochemistry Asteraceae - chemistry Biological and medical sciences Ecdysteroids - chemistry Ecdysteroids - isolation & purification Ecdysteroids - pharmacology Fundamental and applied biological sciences. Psychology Hungary Molecular Structure Nuclear Magnetic Resonance, Biomolecular Other biological molecules Terpenes, steroids. Hormones |
title | Two new ecdysteroids from Serratula wolffii |
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