Two new ecdysteroids from Serratula wolffii

11alpha-Hydroxypoststerone (1) and herkesterone (2), two new natural ecdysteroids, were isolated from the herb Serratula wolffii. The former compound is the first 11-hydroxylated C21 ecdysteroid, while the latter is a new ecdysteroid with a 7,9(11)-dien-6-one chromophore. Their structures were deter...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2004-06, Vol.67 (6), p.1070-1072
Hauptverfasser:	Hunyadi, A, Toth, G, Simon, A, Mak, M, Kele, Z, Mathe, I, Bathori, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Asteraceae - chemistry Biological and medical sciences Ecdysteroids - chemistry Ecdysteroids - isolation & purification Ecdysteroids - pharmacology Fundamental and applied biological sciences. Psychology Hungary Molecular Structure Nuclear Magnetic Resonance, Biomolecular Other biological molecules Terpenes, steroids. Hormones
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Beschreibung
Zusammenfassung:	11alpha-Hydroxypoststerone (1) and herkesterone (2), two new natural ecdysteroids, were isolated from the herb Serratula wolffii. The former compound is the first 11-hydroxylated C21 ecdysteroid, while the latter is a new ecdysteroid with a 7,9(11)-dien-6-one chromophore. Their structures were determined using a combination of spectroscopic techniques.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np030544p