A stereodivergent asymmetric approach to difluorinated aldonic acids

A (bromodifluoromethyl)alkyne has been deployed in a stereoselective route to difluorinated aldonic acid analogues, in which a Sharpless asymmetric dihydroxylation reaction and diastereoisomer separation set the stage for phenyl group oxidation.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2004-07 (13), p.1526-1527
Hauptverfasser:	Audouard, Christophe, Barsukov, Igor, Fawcett, John, Griffith, Gerry A, Percy, Jonathan M, Pintat, Stéphane, Smith, Clive A
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	A (bromodifluoromethyl)alkyne has been deployed in a stereoselective route to difluorinated aldonic acid analogues, in which a Sharpless asymmetric dihydroxylation reaction and diastereoisomer separation set the stage for phenyl group oxidation.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/b405067c