Isolation of 8-hydroxyglycitein and 6-hydroxydaidzein from soybean miso
We isolated from soybean miso 8-hydroxyglycitein and 6-hydroxydaidzein as DPPH-radical scavengers, and elucidated their chemical structures by mass spectrometric, and 1 H- and 13 C-NMR spectrosopic analyses. These compounds showed DPPH-radical scavenging activity as high as that of α-tocopherol, 8-h...
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| Veröffentlicht in: | Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2004-06, Vol.68 (6), p.1372-1374 |
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| container_title | Bioscience, biotechnology, and biochemistry |
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| creator | Hirota, A. (Shizuoka Univ. (Japan)) Inaba, M Chen, Y.C Abe, N Taki, S Yano, M Kawaii, S |
| description | We isolated from soybean miso 8-hydroxyglycitein and 6-hydroxydaidzein as DPPH-radical scavengers, and elucidated their chemical structures by mass spectrometric, and
1
H- and
13
C-NMR spectrosopic analyses. These compounds showed DPPH-radical scavenging activity as high as that of α-tocopherol, 8-hydroxygenistein and 8-hydroxydaidzein. This is the first report of the isolation of 8-hydroxyglycitein from a natural source. |
| doi_str_mv | 10.1271/bbb.68.1372 |
| format | Article |
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1
H- and
13
C-NMR spectrosopic analyses. These compounds showed DPPH-radical scavenging activity as high as that of α-tocopherol, 8-hydroxygenistein and 8-hydroxydaidzein. This is the first report of the isolation of 8-hydroxyglycitein from a natural source.</description><identifier>ISSN: 0916-8451</identifier><identifier>EISSN: 1347-6947</identifier><identifier>DOI: 10.1271/bbb.68.1372</identifier><identifier>PMID: 15215607</identifier><language>eng</language><publisher>Tokyo: Japan Society for Bioscience, Biotechnology, and Agrochemistry</publisher><subject>8-hydroxyglycitein ; 8-hydroxyisoflavone ; Biological and medical sciences ; Biphenyl Compounds ; Cell Proliferation - drug effects ; CELLS ; CHEMICAL STRUCTURE ; DAIDZEIN ; DPPH-radical scavenger ; FLAVONOIDS ; Free Radical Scavengers - chemistry ; Free Radical Scavengers - isolation & purification ; Free Radical Scavengers - pharmacology ; FREE RADICALS ; Fundamental and applied biological sciences. Psychology ; GENISTEIN ; Glycine max - chemistry ; HL-60 cell ; HL-60 Cells ; Humans ; Hydrazines ; HYDROXIDES ; Isoflavones - chemistry ; Isoflavones - isolation & purification ; Isoflavones - pharmacology ; ISOLATION ; MASS SPECTROMETRY ; Molecular Structure ; Nuclear Magnetic Resonance, Biomolecular ; Phytoestrogens - chemistry ; Phytoestrogens - isolation & purification ; Phytoestrogens - pharmacology ; Picrates ; soybean miso ; SOYFOODS</subject><ispartof>Bioscience, biotechnology, and biochemistry, 2004-06, Vol.68 (6), p.1372-1374</ispartof><rights>2004 by Japan Society for Bioscience, Biotechnology, and Agrochemistry 2004</rights><rights>2004 INIST-CNRS</rights><rights>Copyright Japan Science and Technology Agency 2004</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c641t-da276658742369148686fa2df87a5228ed1540429a0ec11079f01264a1d74d603</citedby><cites>FETCH-LOGICAL-c641t-da276658742369148686fa2df87a5228ed1540429a0ec11079f01264a1d74d603</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27915,27916</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16056834$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15215607$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hirota, A. (Shizuoka Univ. (Japan))</creatorcontrib><creatorcontrib>Inaba, M</creatorcontrib><creatorcontrib>Chen, Y.C</creatorcontrib><creatorcontrib>Abe, N</creatorcontrib><creatorcontrib>Taki, S</creatorcontrib><creatorcontrib>Yano, M</creatorcontrib><creatorcontrib>Kawaii, S</creatorcontrib><title>Isolation of 8-hydroxyglycitein and 6-hydroxydaidzein from soybean miso</title><title>Bioscience, biotechnology, and biochemistry</title><addtitle>Biosci Biotechnol Biochem</addtitle><description>We isolated from soybean miso 8-hydroxyglycitein and 6-hydroxydaidzein as DPPH-radical scavengers, and elucidated their chemical structures by mass spectrometric, and
1
H- and
13
C-NMR spectrosopic analyses. These compounds showed DPPH-radical scavenging activity as high as that of α-tocopherol, 8-hydroxygenistein and 8-hydroxydaidzein. This is the first report of the isolation of 8-hydroxyglycitein from a natural source.</description><subject>8-hydroxyglycitein</subject><subject>8-hydroxyisoflavone</subject><subject>Biological and medical sciences</subject><subject>Biphenyl Compounds</subject><subject>Cell Proliferation - drug effects</subject><subject>CELLS</subject><subject>CHEMICAL STRUCTURE</subject><subject>DAIDZEIN</subject><subject>DPPH-radical scavenger</subject><subject>FLAVONOIDS</subject><subject>Free Radical Scavengers - chemistry</subject><subject>Free Radical Scavengers - isolation & purification</subject><subject>Free Radical Scavengers - pharmacology</subject><subject>FREE RADICALS</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>GENISTEIN</subject><subject>Glycine max - chemistry</subject><subject>HL-60 cell</subject><subject>HL-60 Cells</subject><subject>Humans</subject><subject>Hydrazines</subject><subject>HYDROXIDES</subject><subject>Isoflavones - chemistry</subject><subject>Isoflavones - isolation & purification</subject><subject>Isoflavones - pharmacology</subject><subject>ISOLATION</subject><subject>MASS SPECTROMETRY</subject><subject>Molecular Structure</subject><subject>Nuclear Magnetic Resonance, Biomolecular</subject><subject>Phytoestrogens - chemistry</subject><subject>Phytoestrogens - isolation & purification</subject><subject>Phytoestrogens - pharmacology</subject><subject>Picrates</subject><subject>soybean miso</subject><subject>SOYFOODS</subject><issn>0916-8451</issn><issn>1347-6947</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0MFrFTEQBvAgin2tnjwrC1Ivss9MNplkj1K0Vgp60HOY3SR1y-6mJvvQ9a83j_dKQTwFPn4zGT7GXgDfgtDwruu6LZotNFo8YhtopK6xlfox2_AWsDZSwQk7zfmW8xIoeMpOQAlQyPWGXV7lONIyxLmKoTL1j9Wl-Hu9Gdd-WPwwVzS7Cu9jR4P7s09DilOV49p5mqtpyPEZexJozP758T1j3z9--Hbxqb7-cnl18f667lHCUjsSGlEZLUWDLUiDBgMJF4wmJYTxDpTkUrTEfQ_AdRs4CJQETkuHvDljbw5771L8ufN5seX33o8jzT7uskVEiVw2Bb7-B97GXZrLbRakbA3XsoGi3h5Un2LOyQd7l4aJ0mqB2327trRr0dh9u0W_Ou7cdZN3D_ZYZwHnR0C5pzEkmvshPzjkCk0ji8ODG-YQ00S_YhqdXWgdY7ofav5_wcvDYKBo6SYV9_mr4FzxUpPSzV9m1Jrf</recordid><startdate>20040601</startdate><enddate>20040601</enddate><creator>Hirota, A. (Shizuoka Univ. (Japan))</creator><creator>Inaba, M</creator><creator>Chen, Y.C</creator><creator>Abe, N</creator><creator>Taki, S</creator><creator>Yano, M</creator><creator>Kawaii, S</creator><general>Japan Society for Bioscience, Biotechnology, and Agrochemistry</general><general>Japan Society for Bioscience Biotechnology and Agrochemistry</general><general>Oxford University Press</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040601</creationdate><title>Isolation of 8-hydroxyglycitein and 6-hydroxydaidzein from soybean miso</title><author>Hirota, A. (Shizuoka Univ. 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Psychology</topic><topic>GENISTEIN</topic><topic>Glycine max - chemistry</topic><topic>HL-60 cell</topic><topic>HL-60 Cells</topic><topic>Humans</topic><topic>Hydrazines</topic><topic>HYDROXIDES</topic><topic>Isoflavones - chemistry</topic><topic>Isoflavones - isolation & purification</topic><topic>Isoflavones - pharmacology</topic><topic>ISOLATION</topic><topic>MASS SPECTROMETRY</topic><topic>Molecular Structure</topic><topic>Nuclear Magnetic Resonance, Biomolecular</topic><topic>Phytoestrogens - chemistry</topic><topic>Phytoestrogens - isolation & purification</topic><topic>Phytoestrogens - pharmacology</topic><topic>Picrates</topic><topic>soybean miso</topic><topic>SOYFOODS</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hirota, A. (Shizuoka Univ. (Japan))</creatorcontrib><creatorcontrib>Inaba, M</creatorcontrib><creatorcontrib>Chen, Y.C</creatorcontrib><creatorcontrib>Abe, N</creatorcontrib><creatorcontrib>Taki, S</creatorcontrib><creatorcontrib>Yano, M</creatorcontrib><creatorcontrib>Kawaii, S</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Bioscience, biotechnology, and biochemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hirota, A. (Shizuoka Univ. 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1
H- and
13
C-NMR spectrosopic analyses. These compounds showed DPPH-radical scavenging activity as high as that of α-tocopherol, 8-hydroxygenistein and 8-hydroxydaidzein. This is the first report of the isolation of 8-hydroxyglycitein from a natural source.</abstract><cop>Tokyo</cop><pub>Japan Society for Bioscience, Biotechnology, and Agrochemistry</pub><pmid>15215607</pmid><doi>10.1271/bbb.68.1372</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Bioscience, biotechnology, and biochemistry, 2004-06, Vol.68 (6), p.1372-1374 |
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| source | Freely Accessible Japanese Titles - check A-Z of ejournals; J-STAGE Free; MEDLINE; Full-Text Journals in Chemistry (Open access); EZB Electronic Journals Library; Oxford Journals |
| subjects | 8-hydroxyglycitein 8-hydroxyisoflavone Biological and medical sciences Biphenyl Compounds Cell Proliferation - drug effects CELLS CHEMICAL STRUCTURE DAIDZEIN DPPH-radical scavenger FLAVONOIDS Free Radical Scavengers - chemistry Free Radical Scavengers - isolation & purification Free Radical Scavengers - pharmacology FREE RADICALS Fundamental and applied biological sciences. Psychology GENISTEIN Glycine max - chemistry HL-60 cell HL-60 Cells Humans Hydrazines HYDROXIDES Isoflavones - chemistry Isoflavones - isolation & purification Isoflavones - pharmacology ISOLATION MASS SPECTROMETRY Molecular Structure Nuclear Magnetic Resonance, Biomolecular Phytoestrogens - chemistry Phytoestrogens - isolation & purification Phytoestrogens - pharmacology Picrates soybean miso SOYFOODS |
| title | Isolation of 8-hydroxyglycitein and 6-hydroxydaidzein from soybean miso |
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