Interstrand communication between 2'-N-(pyren-1-yl)methyl-2'-amino-LNA monomers in nucleic acid duplexes: directional control and signalling of full complementarity

Very efficient interstrand communication systems in nucleic acid duplexes, based on pyrene excimer formation between 2'-N-(pyren-1-yl)methyl-2'-amino-LNA monomers, demonstrate the versatility of functionalized 2'-amino-LNA monomers for Angstrom-scale chemical engineering.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2004-07 (13), p.1478-1479
Hauptverfasser: Hrdlicka, Patrick J, Babu, B Ravindra, Sørensen, Mads D, Wengel, Jesper
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container_title Chemical communications (Cambridge, England)
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creator Hrdlicka, Patrick J
Babu, B Ravindra
Sørensen, Mads D
Wengel, Jesper
description Very efficient interstrand communication systems in nucleic acid duplexes, based on pyrene excimer formation between 2'-N-(pyren-1-yl)methyl-2'-amino-LNA monomers, demonstrate the versatility of functionalized 2'-amino-LNA monomers for Angstrom-scale chemical engineering.
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source MEDLINE; Royal Society Of Chemistry Journals; Royal Society of Chemistry Journals Archive (1841-2007); Alma/SFX Local Collection
subjects Base Pair Mismatch
Chemical Engineering - methods
DNA Probes
DNA, Complementary - chemistry
Hot Temperature
Molecular Structure
Nucleic Acid Conformation
Nucleic Acid Denaturation
Nucleic Acids - chemistry
Oligonucleotides
Oligonucleotides, Antisense - chemistry
Pyrenes - chemistry
Spectrometry, Fluorescence
title Interstrand communication between 2'-N-(pyren-1-yl)methyl-2'-amino-LNA monomers in nucleic acid duplexes: directional control and signalling of full complementarity
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