Interstrand communication between 2'-N-(pyren-1-yl)methyl-2'-amino-LNA monomers in nucleic acid duplexes: directional control and signalling of full complementarity
Very efficient interstrand communication systems in nucleic acid duplexes, based on pyrene excimer formation between 2'-N-(pyren-1-yl)methyl-2'-amino-LNA monomers, demonstrate the versatility of functionalized 2'-amino-LNA monomers for Angstrom-scale chemical engineering.
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Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2004-07 (13), p.1478-1479 |
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creator | Hrdlicka, Patrick J Babu, B Ravindra Sørensen, Mads D Wengel, Jesper |
description | Very efficient interstrand communication systems in nucleic acid duplexes, based on pyrene excimer formation between 2'-N-(pyren-1-yl)methyl-2'-amino-LNA monomers, demonstrate the versatility of functionalized 2'-amino-LNA monomers for Angstrom-scale chemical engineering. |
doi_str_mv | 10.1039/b404446k |
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source | MEDLINE; Royal Society Of Chemistry Journals; Royal Society of Chemistry Journals Archive (1841-2007); Alma/SFX Local Collection |
subjects | Base Pair Mismatch Chemical Engineering - methods DNA Probes DNA, Complementary - chemistry Hot Temperature Molecular Structure Nucleic Acid Conformation Nucleic Acid Denaturation Nucleic Acids - chemistry Oligonucleotides Oligonucleotides, Antisense - chemistry Pyrenes - chemistry Spectrometry, Fluorescence |
title | Interstrand communication between 2'-N-(pyren-1-yl)methyl-2'-amino-LNA monomers in nucleic acid duplexes: directional control and signalling of full complementarity |
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