Continuation of clozapine treatment: practice makes perfect

Aimed to identify the predictors of drop-out from clozapine treatment by examining the demographic and clinical characteristics of patients registered onclozapine within a 6-month period in one NHS Trust. During the study period,54 patients were registered and began clozapine treatment and 31% had discontinued within 6 months. Two people died and the remainder discontinued because of non-compliance or side-effects. Two factors were predictive: the age of the patient (older patients were more likely to discontinue) and the hospitalwhere the initial registration was made. (Original abstract - amended)