Bioactive Polymers 68-Controlled Release of Neomycine-Furazolidone Bicomponent System from Xanthan Hydrogel
The neomycine-furazolidone-xanthan complex has been synthesized. Neomycine is covalently linked to xanthan, while furazolidone is inserted in the hydrogel formed by the reaction between neomycine and xanthan. The content of neomycine and furazolidone depends on the drug rate in the reaction medium....
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| Veröffentlicht in: | Journal of biomaterials applications 1993-01, Vol.7 (3), p.265-276 |
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| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | The neomycine-furazolidone-xanthan complex has been synthesized. Neomycine is covalently linked to xanthan, while furazolidone is inserted in the hydrogel formed by the reaction between neomycine and xanthan. The content of neomycine and furazolidone depends on the drug rate in the reaction medium. Thus, a zero-order kinetics is obtained for the release of both neomycine and furazolidone in basic medium. The complex's antimicrobial activity is intensified. |
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| ISSN: | 0885-3282 1530-8022 |
| DOI: | 10.1177/088532829300700305 |