Parthenogenetic Stem Cells in Nonhuman Primates

Cibelli et al demonstrate in a study broad differentiation capabilities of primate pluripotent stem cells derived by parthenogenesis. After in vitro maturation for 36 hours, 28 out of 77 primate eggs reached metaphase II.

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2002-02, Vol.295 (5556), p.819-819
Hauptverfasser:	Cibelli, Jose B., Grant, Kathleen A., Chapman, Karen B., Cunniff, Kerrianne, Worst, Travis, Green, Heather L., Walker, Stephen J., Gutin, Philip H., Vilner, Lucy, Tabar, Viviane, Dominko, Tanja, Kane, Jeff, Wettstein, Peter J., Lanza, Robert P., Studer, Lorenz, Vrana, Kent E., West, Michael D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Alcohol Abuse Animals Astrocytes - cytology Blastocyst - cytology Blastocyst - physiology Brevia Cell Culture Techniques Cell Differentiation Cell Division Cell Line Cell lines Cell Separation Cellular differentiation Cloning, Organism Dopamine - metabolism Eggs Embryo, Mammalian - cytology Embryonic stem cells Embryos Individualized Instruction Karyotyping Macaca fascicularis Medical research Mice Mice, SCID Monkeys & apes Neurons Neurons - cytology Ova Parthenogenesis Primate breeding Primates Serotonin - metabolism Somatic cells Stem cells Stem Cells - cytology Stem Cells - physiology Teratoma - pathology Tumor cell line
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Beschreibung
Zusammenfassung:	Cibelli et al demonstrate in a study broad differentiation capabilities of primate pluripotent stem cells derived by parthenogenesis. After in vitro maturation for 36 hours, 28 out of 77 primate eggs reached metaphase II.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.1065637