Pinpointing the centre

The number of active X chromosomes in any cell is determined by a counting mechanism that maintains one X active per two autosome sets and that is postulated to act by blocking one X-inactivation center. Research on X-inactivation is discussed.

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Veröffentlicht in:Nature (London) 1996-01, Vol.379 (6561), p.116-117
1. Verfasser: Lyon, Mary F
Format: Artikel
Sprache:eng
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Zusammenfassung:The number of active X chromosomes in any cell is determined by a counting mechanism that maintains one X active per two autosome sets and that is postulated to act by blocking one X-inactivation center. Research on X-inactivation is discussed.
ISSN:0028-0836
1476-4687
DOI:10.1038/379116a0