H2O2, a Necessary Evil for Cell Signaling

H2O2, a Necessary Evil for Cell Signaling

Once considered lethal to cells, reactive oxygen species are now known to be involved in redox signaling pathways that may contribute to normal cell function as well as disease progression. New areas of research are emerging as to how the cells spatially and temporally channel hydrogen peroxide into...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 2006-06, Vol.312 (5782), p.1882-1883
1. Verfasser: Rhee, Sue Goo
Format: Artikel
Sprache:eng
Schlagworte:
Cellular biology
Chemical compounds
Hydrogen
Oxygen
Signal transduction
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Beschreibung
Zusammenfassung:Once considered lethal to cells, reactive oxygen species are now known to be involved in redox signaling pathways that may contribute to normal cell function as well as disease progression. New areas of research are emerging as to how the cells spatially and temporally channel hydrogen peroxide into specific signaling pathways to achieve desired cellular outcomes.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.1130481