Domain separation in the activation of glycogen phosphorylase alpha

Domain separation in the activation of glycogen phosphorylase alpha

The crystal structure of glycogen phosphorylase a, a cooperative homodimer that catalyzes the degradative phosphorolysis of glycogen, is examined at a resolution of 2.8 angstroms.

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1989-08, Vol.245 (4917), p.528-528
Hauptverfasser: Goldsmith, E.J, Sprang, S.R, Hamlin, R, Xuong, N.-H, Fletterick, R.J
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Enzymes
Glycogen
Oligosaccharides
Phosphorylase
Phosphorylases
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Beschreibung
Zusammenfassung:The crystal structure of glycogen phosphorylase a, a cooperative homodimer that catalyzes the degradative phosphorolysis of glycogen, is examined at a resolution of 2.8 angstroms.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.2756432