Chemical and toxicological characterization of an unresolved complex mixture-rich biodegraded crude oil

Chemical and toxicological characterization of an unresolved complex mixture-rich biodegraded crude oil

Chemical and toxicological characterization of unresolved complex mixtures in the water-soluble fraction of an artificially weathered Norwegian Sea crude oil was determined by a combination of chemical analysis and toxicity testing in fish in vitro bioassays. The water-soluble fraction of the crude...

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Veröffentlicht in:Environmental toxicology and chemistry 2009-09, Vol.28 (9), p.1815-1824
Hauptverfasser: Melbye, Alf G, Brakstad, Odd G, Hokstad, Jorunn N, Gregersen, Inger K, Hansen, Bjørn H, Booth, Andy M, Rowland, Steven J, Tollefsen, Knut E
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Bioassay Toxicity
Bioassays
biodegradability
Biodegradation, Environmental
Chemical analysis
Chromatography, Gas
Chromatography, High Pressure Liquid
Crude oil
cytotoxicity
ecotoxicology
Environmental monitoring
fish
Gas chromatography
gas chromatography-mass spectrometry
Health hazards
hepatocytes
Hepatocytes - drug effects
high performance liquid chromatography
Humans
in vitro studies
Life sciences
Liquid chromatography
liver
Mass spectrometry
Mollusks
naphthalene
Norwegian Sea
Oil spills
Oncorhynchus mykiss
petroleum
Petroleum - analysis
Petroleum - toxicity
Petroleum hydrocarbons
Phenols
Polar compounds
Polycyclic aromatic hydrocarbons
Reservoirs
Salmon
structure-activity relationships
Studies
sulfoxides
Sulfur content
Toxicity
Toxicity testing
Unresolved complex mixture
Water pollution
water solubility
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Zusammenfassung:Chemical and toxicological characterization of unresolved complex mixtures in the water-soluble fraction of an artificially weathered Norwegian Sea crude oil was determined by a combination of chemical analysis and toxicity testing in fish in vitro bioassays. The water-soluble fraction of the crude oil was separated into 14 increasingly polar fractions by preparative high-pressure liquid chromatography. The in vitro toxicity (7-ethoxyresorufin
ISSN:0730-7268
1552-8618
DOI:10.1897/08-545.1