A Method for the Real-Time Observation of Endodermal Cell Behavior on Micropatterned Surfaces

Surface chemistry and geometry have a strong influence on adhesion and proliferation of various cell types, including human embryonic stem cells (ES). Visceral endoderm like cells (END‐2) is an important cell line which induces ES cells to differentiate into cardiomyocytes. In this study, we have in...

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Veröffentlicht in:	Advanced engineering materials 2009-08, Vol.11 (8), p.B106-B113
Hauptverfasser:	Trimbach, David C., Spitkovsky, Dimitry, Garipcan, Bora, Zankovych, Sergiy, Böttinger, Cornelia, Duan, Yaki, Hescheler, Jürgen, Jandt, Klaus D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences cell adhesion cell proliferation Fundamental and applied biological sciences. Psychology gold micropatterning Physical state of matter in biology self assembly surface modification surface topography Tissues, organs and organisms biophysics visceral endoderm (END-2) like cell line
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Beschreibung
Zusammenfassung:	Surface chemistry and geometry have a strong influence on adhesion and proliferation of various cell types, including human embryonic stem cells (ES). Visceral endoderm like cells (END‐2) is an important cell line which induces ES cells to differentiate into cardiomyocytes. In this study, we have investigated the effect of surface chemistry and geometry on the END‐2 cell adhesion and proliferation on gold surface.
ISSN:	1438-1656 1527-2648
DOI:	10.1002/adem.200900083