Conjugated Polymer Nanoparticles for Two‐Photon Imaging of Endothelial Cells in a Tissue Model

Conjugated Polymer Nanoparticles for Two‐Photon Imaging of Endothelial Cells in a Tissue Model

Fabrication and characterization of 8‐nm‐sized conjugated polymer nanoparticles (CPNs) and two‐photon (2P) imaging of CPN labeled endothelial cells in a collagen‐gel‐based microfluidic device is described. CPNs exhibit super brightness and photostability comparable to quantum dots. The hydrophilicit...

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Veröffentlicht in:Advanced materials (Weinheim) 2009-09, Vol.21 (34), p.3492-3496
Hauptverfasser: Rahim, Nur Aida Abdul, McDaniel, William, Bardon, Kevin, Srinivasan, Shalini, Vickerman, Vernella, So, Peter T. C., Moon, Joong Ho
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Conjugated polymers
Conjugated‐polymer nanoparticles
Two‐photon microscopy
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container_end_page 3496
container_issue 34
container_start_page 3492
container_title Advanced materials (Weinheim)
container_volume 21
creator Rahim, Nur Aida Abdul
McDaniel, William
Bardon, Kevin
Srinivasan, Shalini
Vickerman, Vernella
So, Peter T. C.
Moon, Joong Ho
description Fabrication and characterization of 8‐nm‐sized conjugated polymer nanoparticles (CPNs) and two‐photon (2P) imaging of CPN labeled endothelial cells in a collagen‐gel‐based microfluidic device is described. CPNs exhibit super brightness and photostability comparable to quantum dots. The hydrophilicity and non‐toxicity of CPNs enable long‐term monitoring of cells in a tissue model, supporting CPNs' potential in biological and biomedical applications.
doi_str_mv 10.1002/adma.200900416
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source Wiley Online Library Journals Frontfile Complete
subjects Conjugated polymers
Conjugated‐polymer nanoparticles
Two‐photon microscopy
title Conjugated Polymer Nanoparticles for Two‐Photon Imaging of Endothelial Cells in a Tissue Model
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