Conjugated Polymer Nanoparticles for Two‐Photon Imaging of Endothelial Cells in a Tissue Model

Fabrication and characterization of 8‐nm‐sized conjugated polymer nanoparticles (CPNs) and two‐photon (2P) imaging of CPN labeled endothelial cells in a collagen‐gel‐based microfluidic device is described. CPNs exhibit super brightness and photostability comparable to quantum dots. The hydrophilicit...

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Veröffentlicht in:	Advanced materials (Weinheim) 2009-09, Vol.21 (34), p.3492-3496
Hauptverfasser:	Rahim, Nur Aida Abdul, McDaniel, William, Bardon, Kevin, Srinivasan, Shalini, Vickerman, Vernella, So, Peter T. C., Moon, Joong Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Conjugated polymers Conjugated‐polymer nanoparticles Two‐photon microscopy
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Fabrication and characterization of 8‐nm‐sized conjugated polymer nanoparticles (CPNs) and two‐photon (2P) imaging of CPN labeled endothelial cells in a collagen‐gel‐based microfluidic device is described. CPNs exhibit super brightness and photostability comparable to quantum dots. The hydrophilicity and non‐toxicity of CPNs enable long‐term monitoring of cells in a tissue model, supporting CPNs' potential in biological and biomedical applications.
ISSN:	0935-9648 1521-4095
DOI:	10.1002/adma.200900416