Biological activity of silver-doped DLC films

The technique of combined DC metal arc and carbon pulsed arc was used to deposit thin solid films containing up to 6.5 at.% of silver. The microstructure and antibacterial properties of silver-doped diamond-like carbon (DLC) films have been investigated. Silver nanoparticle of flat disk shape locate...

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Veröffentlicht in:	Diamond and related materials 2009-05, Vol.18 (5), p.1006-1009
Hauptverfasser:	Chekan, N.M., Beliauski, N.M., Akulich, V.V., Pozdniak, L.V., Sergeeva, E.K., Chernov, A.N., Kazbanov, V.V., Kulchitsky, V.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Arc deposition Biomaterial Condensed matter: structure, mechanical and thermal properties Cross-disciplinary physics: materials science rheology Diamond-like carbon Exact sciences and technology Fullerenes and related materials diamonds, graphite Materials science Methods of deposition of films and coatings film growth and epitaxy Nanoscale materials and structures: fabrication and characterization Other topics in nanoscale materials and structures Physics Silver doping Specific materials Staphylococcus aureus Structure and morphology thickness Surfaces and interfaces thin films and whiskers (structure and nonelectronic properties) Theory and models of film growth Thin film structure and morphology
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Beschreibung
Zusammenfassung:	The technique of combined DC metal arc and carbon pulsed arc was used to deposit thin solid films containing up to 6.5 at.% of silver. The microstructure and antibacterial properties of silver-doped diamond-like carbon (DLC) films have been investigated. Silver nanoparticle of flat disk shape located inside of an amorphous carbon matrix revealed excellent antibacterial properties concerning Staphylococcus аureus bacteria. Titanium substrates with DLC films doped with silver have an inhibiting effect on growth of some tumors, in particular, on rat neoplastic С6 glioma. This result is new and opens further possibility for application of DLC:Ag composite in medicine.
ISSN:	0925-9635 1879-0062
DOI:	10.1016/j.diamond.2009.02.024