Use of porous ion exchange film for glucose sensing

A rapid response biological and chemical sensor capable of detection to the micromolar level is required for health and environmental monitoring. We have investigated the glucose sensing by using a porous ion exchanger with a three‐dimensional open‐cellular monolith structure. Glucose oxidase (GOD), a typical enzyme, is effectively immobilized on the porous anion exchange film. Addition of glucose to the immobilized GOD results in the production of gluconic acid. The impedance of the ion exchange film increases linearly with glucose concentration, which can be indirectly detected by monitoring gluconic acid concentration. The results demonstrate the potential of the porous anion exchanger as a high performance device for sensitive detection of biological substances. POLYM. ENG. SCI., 2009. © 2009 Society of Plastics Engineers