Antimicrobial Nanotubes Consisting of Ag‐Embedded Peptidic Lipid‐Bilayer Membranes as Delivery Vehicles

Antimicrobial Nanotubes Consisting of Ag‐Embedded Peptidic Lipid‐Bilayer Membranes as Delivery Vehicles

Functional drug‐delivery vehicles consisting of Ag‐embedded bilayer membranes of a peptidic lipid nanotube (LNT) are synthesized. The Ag–LNTs possess antimicrobial ability against E coli, contributing to the release of Ag+ into the aqueous culture. The Ag–LNTs may be applicable to the delivery of DN...

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Veröffentlicht in:Advanced materials (Weinheim) 2009-05, Vol.21 (17), p.1742-1745
Hauptverfasser: Zhou, Yong, Kogiso, Masaki, Asakawa, Masumi, Dong, Sijun, Kiyama, Ryoiti, Shimizu, Toshimi
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drug delivery
lipids
nanotubes
self‐assembly
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container_issue 17
container_start_page 1742
container_title Advanced materials (Weinheim)
container_volume 21
creator Zhou, Yong
Kogiso, Masaki
Asakawa, Masumi
Dong, Sijun
Kiyama, Ryoiti
Shimizu, Toshimi
description Functional drug‐delivery vehicles consisting of Ag‐embedded bilayer membranes of a peptidic lipid nanotube (LNT) are synthesized. The Ag–LNTs possess antimicrobial ability against E coli, contributing to the release of Ag+ into the aqueous culture. The Ag–LNTs may be applicable to the delivery of DNA or biotechnological drugs that are usually sensitive to changes in their surroundings.
doi_str_mv 10.1002/adma.200803072
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subjects drug delivery
lipids
nanotubes
self‐assembly
title Antimicrobial Nanotubes Consisting of Ag‐Embedded Peptidic Lipid‐Bilayer Membranes as Delivery Vehicles
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