Antimicrobial Nanotubes Consisting of Ag‐Embedded Peptidic Lipid‐Bilayer Membranes as Delivery Vehicles

Antimicrobial Nanotubes Consisting of Ag‐Embedded Peptidic Lipid‐Bilayer Membranes as Delivery Vehicles

Functional drug‐delivery vehicles consisting of Ag‐embedded bilayer membranes of a peptidic lipid nanotube (LNT) are synthesized. The Ag–LNTs possess antimicrobial ability against E coli, contributing to the release of Ag+ into the aqueous culture. The Ag–LNTs may be applicable to the delivery of DN...

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Veröffentlicht in:Advanced materials (Weinheim) 2009-05, Vol.21 (17), p.1742-1745
Hauptverfasser: Zhou, Yong, Kogiso, Masaki, Asakawa, Masumi, Dong, Sijun, Kiyama, Ryoiti, Shimizu, Toshimi
Format: Artikel
Sprache:eng
Schlagworte:
drug delivery
lipids
nanotubes
self‐assembly
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Zusammenfassung:Functional drug‐delivery vehicles consisting of Ag‐embedded bilayer membranes of a peptidic lipid nanotube (LNT) are synthesized. The Ag–LNTs possess antimicrobial ability against E coli, contributing to the release of Ag+ into the aqueous culture. The Ag–LNTs may be applicable to the delivery of DNA or biotechnological drugs that are usually sensitive to changes in their surroundings.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200803072