Electrocatalytic Behavior and Amperometric Detection of Morphine on ITO Electrode Modified with Directly Electrodeposited Gold Nanoparticles

A gold nanoparticles (AuNPs) modified indium tin oxide (ITO) film coated glass electrode was prepared via a novel electrochemical deposition technique. The UV‐visible spectrum and SEM indicated that the AuNPs on ITO electrode surface were spherical shape and quite symmetric distributed. The modified electrode exhibited excellent catalytic activity for the oxidation of morphine (MO). At optimal experimental condition, the oxidation current was responsive with the MO concentrations ranging from 8.0×10−7 to 1.6×10−5 M, the detection limit was 2.1×10 –7 M. The modified electrode also exhibited high stability and reproducibility. The average recoveries of detection MO in human urine were ranged between 91.95% and 92.23%, and the RSD was less than 3.68% (n=5).