3C-SiC Nanocrystals as Fluorescent Biological Labels

Silicon carbide nanocrystals are water‐soluble, chemically inert, and highly fluorescent, and they may be idealas biological labels. After the uptake of3C–SiC nanocrystals, human fetal osteoblast (hFOB) cells exhibit brightgreen–yellow fluorescence (see image).The nanoparticles show high resistancea...

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Veröffentlicht in:	Small (Weinheim an der Bergstrasse, Germany) Germany), 2008-08, Vol.4 (8), p.1058-1062
Hauptverfasser:	Fan, Jiyang, Li, Hongxia, Jiang, Jiang, So, Leo K. Y., Lam, Yun Wah, Chu, Paul K.
Format:	Artikel
Sprache:	eng
Schlagworte:	biological labeling Carbon Compounds, Inorganic - chemistry Carbon Compounds, Inorganic - toxicity Cell Line Cells, Cultured Endocytosis - drug effects Fetus fluorescence Fluorescent Dyes - chemistry HeLa Cells Humans nanoparticles Nanoparticles - chemistry Nanoparticles - toxicity Nanoparticles - ultrastructure Osteoblasts - chemistry Osteoblasts - drug effects Quantum Dots silicon carbide Silicon Compounds - chemistry Silicon Compounds - toxicity Spectrometry, Fluorescence Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Staining and Labeling
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Beschreibung
Zusammenfassung:	Silicon carbide nanocrystals are water‐soluble, chemically inert, and highly fluorescent, and they may be idealas biological labels. After the uptake of3C–SiC nanocrystals, human fetal osteoblast (hFOB) cells exhibit brightgreen–yellow fluorescence (see image).The nanoparticles show high resistanceagainst photobleaching with no significant cytotoxicity.
ISSN:	1613-6810 1613-6829
DOI:	10.1002/smll.200800080