In situ fabrication of a poly-acrylamide membrane in a microfluidic channel
We present a novel technological approach for the in situ realization of a micron-thin poly-acrylamide membrane in the center of a microfluidic channel. The membrane is formed by interfacial polymerization of an inner stream of monomer solution in between two streams of initiator/catalyst solution i...
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Veröffentlicht in: | Microelectronic engineering 2008-05, Vol.85 (5-6), p.1083-1085 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | We present a novel technological approach for the in situ realization of a micron-thin poly-acrylamide membrane in the center of a microfluidic channel. The membrane is formed by interfacial polymerization of an inner stream of monomer solution in between two streams of initiator/catalyst solution in a hydrodynamic focusing chip. 20μm thick SU-8 structures are used to replicate the chip in poly dimethylsiloxane (PDMS). The chip is fitted within an adaptor allowing easy fluidic connections, temperature control and optical monitoring under a microscope. With this system, we can easily tune the internal stream width from 5 to 100μm, by varying the internal/external flow ratio. |
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ISSN: | 0167-9317 1873-5568 |
DOI: | 10.1016/j.mee.2007.12.050 |