SU-8 2000 rendered cytocompatible for neuronal bioMEMS applications

SU-8 2000 rendered cytocompatible for neuronal bioMEMS applications

Microfabrication advances have resulted in small, cheap, and precise devices for biological microelectromechanical systems (bioMEMS). SU‐8/SU‐8 2000 is an attractive material for these applications because of its high‐aspect ratio fabrication capability, dielectric properties, and thermochemical sta...

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Veröffentlicht in:Journal of Biomedical Materials Research Part B 2009-04, Vol.89A (1), p.138-151
Hauptverfasser: Vernekar, Varadraj N., Cullen, D. Kacy, Fogleman, Nick, Choi, Yoonsu, García, Andrés J., Allen, Mark G., Brewer, Gregory J., LaPlaca, Michelle C.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cell Culture Techniques
Cell Survival
Cells, Cultured
Coated Materials, Biocompatible - chemistry
Epoxy Compounds - chemistry
Epoxy Compounds - toxicity
Female
Materials Testing
MEMS
Micro-Electrical-Mechanical Systems
microfabrication
neurons
Neurons - cytology
Neurons - drug effects
Neurons - metabolism
Polymers - chemistry
Polymers - toxicity
Pregnancy
process optimization
Rats
Rats, Sprague-Dawley
Surface Properties
toxicity
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Zusammenfassung:Microfabrication advances have resulted in small, cheap, and precise devices for biological microelectromechanical systems (bioMEMS). SU‐8/SU‐8 2000 is an attractive material for these applications because of its high‐aspect ratio fabrication capability, dielectric properties, and thermochemical stability. Despite these advantages, the potential toxicity of SU‐8 2000 may limit its use in cell‐based applications. We show that
ISSN:1549-3296
1552-4965
1552-4981
DOI:10.1002/jbm.a.31839