Air plasma coupled with antibody-conjugated nanoparticles: a new weapon against cancer

Ambient air plasmas have been known to kill cancer cells. To enhance selectivity we have used antibody-conjugated nanoparticles. We achieved five times enhancement of melanoma cell death over the case of the plasma alone by using an air plasma with gold nanoparticles bound to anti-FAK antibodies. Ou...

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Veröffentlicht in:Journal of physics. D, Applied physics Applied physics, 2009-02, Vol.42 (3), p.032005-032005 (5)
Hauptverfasser: Kim, G C, Kim, G J, Park, S R, Jeon, S M, Seo, H J, Iza, F, Lee, J K
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Sprache:eng
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Zusammenfassung:Ambient air plasmas have been known to kill cancer cells. To enhance selectivity we have used antibody-conjugated nanoparticles. We achieved five times enhancement of melanoma cell death over the case of the plasma alone by using an air plasma with gold nanoparticles bound to anti-FAK antibodies. Our results show that this new interdisciplinary technique has enormous potential for use as a complement to conventional therapies.
ISSN:0022-3727
1361-6463
DOI:10.1088/0022-3727/42/3/032005