Optimization of systemic nasal drug delivery with pharmaceutical excipients
The nasal drug route provides a viable alternative for many drugs which are presently administered via parenteral and oral routes. Nasal drug absorption is optimized by improving on formulation excipients, designing various types of novel nasal dosage forms, and understanding the mechanisms of nasal...
Gespeichert in:
Veröffentlicht in: | Advanced drug delivery reviews 1998-01, Vol.29 (1), p.117-133 |
---|---|
Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 133 |
---|---|
container_issue | 1 |
container_start_page | 117 |
container_title | Advanced drug delivery reviews |
container_volume | 29 |
creator | Behl, C.R Pimplaskar, H.K Sileno, A.P Xia, W.J Gries, W.J deMeireles, J.C Romeo, V.D |
description | The nasal drug route provides a viable alternative for many drugs which are presently administered via parenteral and oral routes. Nasal drug absorption is optimized by improving on formulation excipients, designing various types of novel nasal dosage forms, and understanding the mechanisms of nasal drug absorption. |
doi_str_mv | 10.1016/S0169-409X(97)00064-1 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_33447805</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0169409X97000641</els_id><sourcerecordid>33447805</sourcerecordid><originalsourceid>FETCH-LOGICAL-c479t-8e74dff4e252922bd7cf0d1fa3d5252911aeeab2a6addc6c51c942caa80910b43</originalsourceid><addsrcrecordid>eNqFkUFP3DAQha2qVXfZ9icU5VTBIeCxnTg-IYRaQCBxoJV6s7z2pGuUbILtANtfT8KiihN7mZFG37wnvUfIN6BHQKE8vh2HygVVfw6UPKSUliKHD2QOlWR5xZT4SOb_kRnZi_GOUmCypJ_JDGjFZVHxObm66ZNv_T-TfLfOujqLm5iw9TZbm2iazIXhb-aw8Q8YNtmjT6usX5nQGotD8nYk8Mn63uM6xS_kU22aiF9f94L8_vnj19lFfn1zfnl2ep1bIVXKK5TC1bVAVjDF2NJJW1MHteGumE4ABtEsmSmNc7a0BVglmDWmogroUvAF-b7V7UN3P2BMuvXRYtOYNXZD1JwLISta7AQZcChLDiN48C4IVaE4E4WcNIstakMXY8Ba98G3Jmw0UD01o1-a0VPsWkn90oyeLPZfLYZli-7N17aKETjZAjhG9-Ax6GjHWC06H9Am7Tq_w-IZUIyfFQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1859324575</pqid></control><display><type>article</type><title>Optimization of systemic nasal drug delivery with pharmaceutical excipients</title><source>Elsevier ScienceDirect Journals</source><creator>Behl, C.R ; Pimplaskar, H.K ; Sileno, A.P ; Xia, W.J ; Gries, W.J ; deMeireles, J.C ; Romeo, V.D</creator><creatorcontrib>Behl, C.R ; Pimplaskar, H.K ; Sileno, A.P ; Xia, W.J ; Gries, W.J ; deMeireles, J.C ; Romeo, V.D</creatorcontrib><description>The nasal drug route provides a viable alternative for many drugs which are presently administered via parenteral and oral routes. Nasal drug absorption is optimized by improving on formulation excipients, designing various types of novel nasal dosage forms, and understanding the mechanisms of nasal drug absorption.</description><identifier>ISSN: 0169-409X</identifier><identifier>EISSN: 1872-8294</identifier><identifier>DOI: 10.1016/S0169-409X(97)00064-1</identifier><identifier>PMID: 10837583</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Absorption ; Absorption enhancers ; Absorption factors ; Absorption optimizers ; Bile salts ; Gels ; Intranasal drug delivery ; Nasal delivery ; Nasal gels ; Nasal powders ; Nasal solutions ; Pharmacokinetics ; Physical chemical properties ; Powders ; Salts</subject><ispartof>Advanced drug delivery reviews, 1998-01, Vol.29 (1), p.117-133</ispartof><rights>1998 Elsevier Science B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c479t-8e74dff4e252922bd7cf0d1fa3d5252911aeeab2a6addc6c51c942caa80910b43</citedby><cites>FETCH-LOGICAL-c479t-8e74dff4e252922bd7cf0d1fa3d5252911aeeab2a6addc6c51c942caa80910b43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0169409X97000641$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10837583$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Behl, C.R</creatorcontrib><creatorcontrib>Pimplaskar, H.K</creatorcontrib><creatorcontrib>Sileno, A.P</creatorcontrib><creatorcontrib>Xia, W.J</creatorcontrib><creatorcontrib>Gries, W.J</creatorcontrib><creatorcontrib>deMeireles, J.C</creatorcontrib><creatorcontrib>Romeo, V.D</creatorcontrib><title>Optimization of systemic nasal drug delivery with pharmaceutical excipients</title><title>Advanced drug delivery reviews</title><addtitle>Adv Drug Deliv Rev</addtitle><description>The nasal drug route provides a viable alternative for many drugs which are presently administered via parenteral and oral routes. Nasal drug absorption is optimized by improving on formulation excipients, designing various types of novel nasal dosage forms, and understanding the mechanisms of nasal drug absorption.</description><subject>Absorption</subject><subject>Absorption enhancers</subject><subject>Absorption factors</subject><subject>Absorption optimizers</subject><subject>Bile salts</subject><subject>Gels</subject><subject>Intranasal drug delivery</subject><subject>Nasal delivery</subject><subject>Nasal gels</subject><subject>Nasal powders</subject><subject>Nasal solutions</subject><subject>Pharmacokinetics</subject><subject>Physical chemical properties</subject><subject>Powders</subject><subject>Salts</subject><issn>0169-409X</issn><issn>1872-8294</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><recordid>eNqFkUFP3DAQha2qVXfZ9icU5VTBIeCxnTg-IYRaQCBxoJV6s7z2pGuUbILtANtfT8KiihN7mZFG37wnvUfIN6BHQKE8vh2HygVVfw6UPKSUliKHD2QOlWR5xZT4SOb_kRnZi_GOUmCypJ_JDGjFZVHxObm66ZNv_T-TfLfOujqLm5iw9TZbm2iazIXhb-aw8Q8YNtmjT6usX5nQGotD8nYk8Mn63uM6xS_kU22aiF9f94L8_vnj19lFfn1zfnl2ep1bIVXKK5TC1bVAVjDF2NJJW1MHteGumE4ABtEsmSmNc7a0BVglmDWmogroUvAF-b7V7UN3P2BMuvXRYtOYNXZD1JwLISta7AQZcChLDiN48C4IVaE4E4WcNIstakMXY8Ba98G3Jmw0UD01o1-a0VPsWkn90oyeLPZfLYZli-7N17aKETjZAjhG9-Ax6GjHWC06H9Am7Tq_w-IZUIyfFQ</recordid><startdate>19980105</startdate><enddate>19980105</enddate><creator>Behl, C.R</creator><creator>Pimplaskar, H.K</creator><creator>Sileno, A.P</creator><creator>Xia, W.J</creator><creator>Gries, W.J</creator><creator>deMeireles, J.C</creator><creator>Romeo, V.D</creator><general>Elsevier B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope></search><sort><creationdate>19980105</creationdate><title>Optimization of systemic nasal drug delivery with pharmaceutical excipients</title><author>Behl, C.R ; Pimplaskar, H.K ; Sileno, A.P ; Xia, W.J ; Gries, W.J ; deMeireles, J.C ; Romeo, V.D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c479t-8e74dff4e252922bd7cf0d1fa3d5252911aeeab2a6addc6c51c942caa80910b43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Absorption</topic><topic>Absorption enhancers</topic><topic>Absorption factors</topic><topic>Absorption optimizers</topic><topic>Bile salts</topic><topic>Gels</topic><topic>Intranasal drug delivery</topic><topic>Nasal delivery</topic><topic>Nasal gels</topic><topic>Nasal powders</topic><topic>Nasal solutions</topic><topic>Pharmacokinetics</topic><topic>Physical chemical properties</topic><topic>Powders</topic><topic>Salts</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Behl, C.R</creatorcontrib><creatorcontrib>Pimplaskar, H.K</creatorcontrib><creatorcontrib>Sileno, A.P</creatorcontrib><creatorcontrib>Xia, W.J</creatorcontrib><creatorcontrib>Gries, W.J</creatorcontrib><creatorcontrib>deMeireles, J.C</creatorcontrib><creatorcontrib>Romeo, V.D</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Advanced drug delivery reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Behl, C.R</au><au>Pimplaskar, H.K</au><au>Sileno, A.P</au><au>Xia, W.J</au><au>Gries, W.J</au><au>deMeireles, J.C</au><au>Romeo, V.D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Optimization of systemic nasal drug delivery with pharmaceutical excipients</atitle><jtitle>Advanced drug delivery reviews</jtitle><addtitle>Adv Drug Deliv Rev</addtitle><date>1998-01-05</date><risdate>1998</risdate><volume>29</volume><issue>1</issue><spage>117</spage><epage>133</epage><pages>117-133</pages><issn>0169-409X</issn><eissn>1872-8294</eissn><abstract>The nasal drug route provides a viable alternative for many drugs which are presently administered via parenteral and oral routes. Nasal drug absorption is optimized by improving on formulation excipients, designing various types of novel nasal dosage forms, and understanding the mechanisms of nasal drug absorption.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>10837583</pmid><doi>10.1016/S0169-409X(97)00064-1</doi><tpages>17</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0169-409X |
ispartof | Advanced drug delivery reviews, 1998-01, Vol.29 (1), p.117-133 |
issn | 0169-409X 1872-8294 |
language | eng |
recordid | cdi_proquest_miscellaneous_33447805 |
source | Elsevier ScienceDirect Journals |
subjects | Absorption Absorption enhancers Absorption factors Absorption optimizers Bile salts Gels Intranasal drug delivery Nasal delivery Nasal gels Nasal powders Nasal solutions Pharmacokinetics Physical chemical properties Powders Salts |
title | Optimization of systemic nasal drug delivery with pharmaceutical excipients |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T08%3A54%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Optimization%20of%20systemic%20nasal%20drug%20delivery%20with%20pharmaceutical%20excipients&rft.jtitle=Advanced%20drug%20delivery%20reviews&rft.au=Behl,%20C.R&rft.date=1998-01-05&rft.volume=29&rft.issue=1&rft.spage=117&rft.epage=133&rft.pages=117-133&rft.issn=0169-409X&rft.eissn=1872-8294&rft_id=info:doi/10.1016/S0169-409X(97)00064-1&rft_dat=%3Cproquest_cross%3E33447805%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1859324575&rft_id=info:pmid/10837583&rft_els_id=S0169409X97000641&rfr_iscdi=true |