New liposome development: Lipid/DNA complexes as an intermediate in the preparation of particles for gene transfer: an alternative to cationic liposome/DNA aggregates
When cationic liposomes are mixed with plasmid DNA an aggregation reaction occurs. The heterogeneous membrane structures which arise following this reaction are dependent on liposomal lipid composition, liposome/DNA ratio as well as the presence of added salts or proteins. The resulting structures a...
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Veröffentlicht in: | Advanced drug delivery reviews 1997-03, Vol.24 (2-3), p.275-290 |
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Format: | Artikel |
Sprache: | eng |
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